All MedChem Seminars

The Medicinal Chemistry Department seminars involve a mix of prominent researchers from both academic institutions and industry presenting research at the forefront of Medicinal Chemistry (broadly defined). They also include presentations from our own students (dissertation defenses & research seminars). The seminars are held on Thursday, weekly at 4:00pm in room 2548 NUB at the College of Pharmacy unless otherwise stated. Select a semester from the drop-down menu below to browse the schedule.

	September 13, 2012 4:00pm 2548 CC Little	Mi Hee Lim, PhD Assistant Professor University of Michigan, Department of Chemistry Small Molecules as Chemical Tools and Potential Therapeutics for Alzheimer's Disease
	September 20, 2012 4:00pm 2548 CC Little	Gunda Georg, PhD Professor and Department Head, Robert Vince Endowed Chair, McKnight Presidential Chair in Medicinal Chemistry University of Minnesota Academic drug discovery projects: Minnelide for pancreatic cancer chemotherapy and Gamendazole for male contraception
	October 4, 2012 4:00pm 2548 CC Little	Victor Marquez, PhD Rackham Centennial Speaker Scientist Emeritus, National Cancer Institute Conformationally Locked Nucleosides as Tools to Unlock Nature's Secrets
	October 16, 2012 4:00pm 2548 CC Little	Elizabeth Girnys PhD Candidate-Dissertation Defense University of Michigan Synthesis and Structure-Activity Relationships of Novel Direct Thrombin Inhibitors based on Pentapeptide FM 19
	October 18, 2012 4:00pm 2548 CC Little	Steven J. Metallo, PhD Associate Professor Georgetown University, Department of Chemistry Intrinsically disordered proteins as potential drug targets
	October 25, 2012 4:00pm 2548 CC Little	Mark Kelley, PhD Associate Director-Herman B. Wells Center for Pediatric Research Indiana University School of Medicine The DNA repair and redox signaling protein APE1/Ref-1: Target for cancer therapeutics, chemo-induced peripheral neuropathy and other indications
	November 8, 2012 4:00pm 2548 CC Little	Paul L. Richardson, PhD Principal Research Scientist Abbott Laboratories; Chicago, IL Modular Probes: Time-Resolved Fluorescence-Resonance Energy Transfer (TR-FRET) for High-Throughput Screening (HTS) and Other Applications
	November 15, 2012 4:00pm 2548 CC Little	Ronald Breslow, PhD John G. Topliss Lecture, Speaker Professor of Chemistry and Biology, Columbia University A Hypothesis-Driven Anticancer Path from Cells to Humans
	December 11, 2012 4:00pm 2548 CC Little	Timor Baasov, PhD Professor, Schulich Faculty of Chemistry in Technion Israel Institute of Technology, Israel To Fix Nature's Mistakes: Repairing Human Faulty Genes by Sugar-Based Small Molecules
	January 7, 2013 4:00pm 2548 CC Little	Kamil Godula, PhD Project Scientist, Lawrence Berkeley National Laboratory Synthetic Mucin Mimetics: Nanoscale Tools for Glycobiology
	January 10, 2013 4:00pm 2548 CC Little	Tamara Hendrickson, PhD Associate Professor, Department of Chemistry Wayne State University Discovery of new bacterial enzymes in protein biosynthesis
	January 14, 2013 4:00pm 2548 CC Little	Amanda Garner, PhD Senior Research Associate Janda Laboratory, The Scripps Research Institute Expanding the Scope of Organic Chemistry: Applications in Assay Design and Chemical Probe Discovery
	January 17, 2013 4:00pm 2548 CC Little	Rachel A. Powers, PhD Associate Professor of Chemistry Grand Valley State University Substrate specificity in class D Î²-lactamases: A structure based comparison of OXA-1 and OXA-24 with oxacillin bound
	January 22, 2013 4:00pm 2548 CC Little	David Minh Postdoctoral Research Associate Duke University, Department of Chemistry Computational Molecular Recognition - Prediction of Noncovalent Binding Affinities using Implicit Ligand Theory
	January 24, 2013 4:00pm 2548 CC Little	Ron Jenkins PhD Candidate-Dissertation Defense University of Michigan Phage Display as a Tool for Probing Lipid A Biosynthesis.
	February 4, 2013 4:00pm 2548 CC Little	Jiaoyang Jiang, PhD Postoctoral Fellow Harvard Medical School Mechanism, Inhibition & Proteolytic Activity of Human O-GlcNAc Transferase
	February 28, 2013 4:00pm 2548 CC Little	Ching-Shih Chen, PhD Professor of Medicinal Chemistry and Pharmacognosy Ohio State University Therapeutic Development Targeting Tumor Microenvironment
	March 1, 2013 4:00pm 2548 CC Little	Peter Ung Medicinal Chemistry Ph.D. Candidate University of Michigan Incorporation of Protein Flexibility in Structure-Based Drug Discovery of HIV-1 Protease and Bacterial Hsp70 Chaperone
	March 14, 2013 4:00pm 2548 CC Little	Kevin D. Walker, PhD Department of Chemistry Michigan State University Mechanisms of Enzymes Involved in the Biocatalysis of Paclitaxel
	March 28, 2013 4:00pm 2548 CC Little	David Colby, PhD Assistant Professor of Medicinal Chemistry Purdue University Synthesis and Biological Evaluation of Difluoromethyl Ketones as GABA agonists
	April 11, 2013 4:00pm 2548 CC Little	William P. Schiemann Co-Director and Associate Professor, Comprehensive Cancer Center Case Western Reserve University Oncogenic TGF-Î² Signaling and EMT Programs in Metastatic Breast Cancer
	April 18, 2013 4:00pm 2548 CC Little	Charalampos (Babis) Kalodimos, PhD Department of Chemistry and Chemical Biology Rutgers University Dynamic Activation of Protein Function
	May 16, 2013 4:00pm 2548 CC Little	Gloria Komazin-Meredith, PhD Leroy B. Townsend Symposium Lecturer Senior Scientist, Microbiotix Inc Methylenecyclopropane Analogues of Nucleosides as Broad Spectrum Anti-Herpes Agents
	July 25, 2013 2pm 2548 CC Little	Jessica Anand Medicinal Chemistry Ph. D. Candidate-Dissertation Defense University of Michigan The Mu and Delta Opioid Receptors: Mixed Efficacy Ligands and Receptor Trafficking Faculty Host: Henry I. Mosberg ( [email protected] ) 764-8117
	August 12, 2013 4:00pm 2548 CC Little	Kyle Bolduc Medicinal Chemistry Ph. D. Candidate-Dissertation Defense University of Michigan Development of Synthetic and Biocatalytic Methods for the Chemoenzymatic Production of Novel Cryptophycin Anticancer Agents
	August 15, 2013 4:00pm 2548 CC Little	Bryan Yestrepsky Medicinal Chemistry Ph. D. Candidate-Dissertation Defense University of Michigan Development of a Novel Class of Multifunctional Virulence-Attenuating Antibiotics
	September 3, 2013 2:30-3:30pm 2548 CC Little	Lauren Dixon Mishra Medicinal Chemistry Ph.D. Candidate University of Michigan Molecular Recognition of small Molecules by Rho-associated Protein Kinase Faculty Host: Gary D. Glick ( [email protected] ) 734-764-4548
	October 31, 2013 4:00pm 2548 CC Little	Richard A. Gibbs, PhD Associate Dean for Graduate Programs, Professor of Medicinal Chemistry and Molecular Pharmacology Purdue University Inhibitors of Isoprenylcysteine Carboxyl Methyltransferase as Potential Treatments for Pancreatic Cancer Faculty Host: Matt Soellner ( [email protected] ) 734-615-2767 Speaker Website
	November 14, 2013 4:00pm 2548 CC Little	Alejandra Yep-Rodriguez, PhD Assistant Research Scientist, Department of Microbiology and Immunology University of Michigan University of Michigan A high-throughput screen for small molecule inhibitors of iron acquisition in uropathogenic E. coli Faculty Host: Hollis Showalter ( [email protected] ) 734-764-5504 Speaker Website
	November 21, 2013 4:00pm 2548 CC Little	Christopher M. Waters, PhD Assistant Professor, Department of Microbiology and Molecular Genetics Michigan State University TBA Targeting cyclic di-GMP signaling to prevent bacterial biofilm formation Faculty Host: Amanda Garner ( [email protected] ) 734-763-2654 Speaker Website
	December 5, 2013 4:00pm BSRB Kahn Auditorium	John G. Topliss Lecture-Paul S. Anderson, Ph.D. Retired VP of Chemistry (Merck) and Senior VP for Drug Discovery (Bristol-Myers Squibb) A Perspective on Drug Discovery Faculty Host: Scott Larsen ( [email protected] ) 734-615-0454
	January 16, 2014 4:00pm 2548 CC Little	David Cech MedChem Graduate Student, University of Michigan Third Year Seminar Structure, biochemical, and regulation studies of D-arabinose-5-phosphate isomerase
	January 22, 2014 1:00 p.m. Rackham Fourth Floor, East Conference Room	Fardohkt Abulwerdi Medicinal Chemistry Ph.D. Candidate-Dissertation Defense University of Michigan Structure-based design, synthesis and evaluation of novel and selective small-molecule inhibitors of the anti-apoptotic protein Mcl-1 Faculty Host: Zaneta Nikolovska-Coleska and Hollis Showalter
	January 23, 2014 4:00pm 2548 CC Little	Jordan Clark MedChem Graduate Student, University of Michigan Third Year Seminar Inherent versus Induced Protein Flexibility
	January 30, 2014 4:00pm 2548 CC Little	Chris Holt MedChem Graduate Student, University of Michigan Third Year Seminar A Unique CMP-Kdo Synthetase from Shewanella Oneidensis
	February 6, 2014 4:00pm 2548 CC Little	Taylor Johnson MedChem Graduate Student, University of Michigan Third Year Seminar Using bivalent inhibitors to probe protein tyrosine kinase signaling in cells
	February 13, 2014 4:00pm 2548 CC Little	Nathanael Gray, PhD Professor of Biological Chemistry and Molecular Pharmacology Harvard Medical School, Dana Farber Cancer Institute TBA Faculty Host: Matt Soellner ( [email protected] ) 734-615-2767 Speaker Website
	February 20, 2014 4:00pm 2548 CC Little	Christine S. Chow, PhD Professor and Associate Dean, Department of Chemistry Wayne State University TBA Faculty Host: Amanda Garner ( [email protected] ) 734-763-2654 Speaker Website
	February 27, 2014 4:00pm 2548 CC Little	Aaron Bender MedChem Graduate Student, University of Michigan Third Year Seminar Synthesis of mixed efficacy opioid peptidomimetics
	March 10, 2014 2:00 pm Rackham Graduate School, East Conference Room, Fourth Floor	Kamali Sripathi Medicinal Chemistry Ph.D. Candidate-Dissertation Defense University of Michigan Structural Dynamics of the Hepatitis Delta Virus and Hairpin Ribozymes: Implications for Function Faculty Host: Nils Walter, Ph.D. ( [email protected] )
	March 13, 2014 4:00pm 2548 CC Little	Michael J. McLeish, PhD Associate Professor, Chemistry, Department of Chemistry and Chemical Biology Indiana University-Purdue University, Indianapolis TBA Speaker Website
	March 27, 2014 4:00pm 2548 CC Little	Tim S. Bugni, PhD Assistant Professor, Division of Pharmaceutical Sciences School of Pharmacy; University of Wisconsin, Madison Metabolomics for Natural Products Discovery and Library Design Faculty Host: David Sherman ( [email protected] ) 734-615-9907 Speaker Website
	April 10, 2014 4:00pm 2548 CC Little	Dr. Clifton Barry III, PhD Section Chief and Senior Investigator (Tenured), Tuberculosis Research Section, National Institute of Allergy and Infectious Diseases National Institutes of Health The evolution of rifampicin resistance in Mycobacterium tuberculosis: fitness and compensation Faculty Host: George Garcia ( [email protected] ) 734-764-2202 Student Host: Max Stefan ( [email protected] ) 734-647-3239 Speaker Website
	April 17, 2014 4:00pm 2548 CC Little	Dennis C. Liotta, PhD Samuel Candler Dobbs Professor Department of Chemistry, Emory University The Role of CXCR4 Modulators in Controlling HIV Entry, Stem Cell Mobilization and Certain Types of Cancer Faculty Host: Shaomeng Wang ( [email protected] ) 734-615-0632 Speaker Website Speaker Abstract
	May 22, 2014 Lecture: 11:00am, Reception Preceding Lecture: 10:15am Lecture Location:1544 CC Little Bldg.; Reception Location: College of Pharmacy Front Lobby, 428 Church St.	Geoffrey C. Hoops, Ph.D.; Ninth Annual Leroy B. Townsend Symposium Professor, Chemistry Department Butler University Probing the Enzymatic Activity of the Rv0045c Esterase from M. Tuberculosis: A Research Model for Undergraduate Biochemistry Education Faculty Host: George A. Garcia ( [email protected] ) 647-8429 Speaker Website Speaker Abstract
	July 2, 2014 4:00pm 2548 CC Little	Ghanakota Venkateshwar Rao, PhD The Chairman, Board of Studies in Chemistry and Biochemistry and Professor of Organic Chemistry Departments of Chemistry and Biochemistry, Kakatiya University, Warangal, Telangana, India Microbial degradation of aromatic organic pollutants – A study of dead-end metabolites including the stereochemical mechanistic studies of cycloisomerase enzyme and their products using deuterium labelled precursors Faculty Host: Heather Carlson ( [email protected] ) 615-6841 Student Host: Phani Ghanakota ( [email protected] ) Speaker Abstract
	July 29, 2014 2:00 pm 2548 CC Little	Leah Makley Medicinal Chemistry Ph.D. Candidate University of Michigan Oral Dissertation Defense, "Chemical Approaches for ‘Undruggable’ Targets: The Discovery of Ligands for Small Heat Shock Proteins." Faculty Host: Jason Gestwicki and Heather Carlson ( [email protected] ) 615-6841
	August 6, 2014 10:00am 1544 CC Little Building	Meghan E. Breen Medicinal Chemistry Ph.D. Candidate University of Michigan Oral Dissertation Defense,"Substrate-Competitive Inhibitors of c-Src Kinase" Faculty Host: Matt Soellner ( [email protected] ) 615-2767
	August 20, 2014 1:00pm 2548 CC Little	Scott Barraza Medicinal Chemistry Ph.D. Candidate University of Michigan Oral Dissertation Defense, "Development of Novel Small Molecule Inhibitors of Neurotropic Alphavirus Replication" Faculty Host: Scott Larsen ( [email protected] ) 615-0454
	August 28, 2014 3:00pm 2548 CC Little	Janice Sindac Medicinal Chemistry Ph.D. Candidate University of Michigan Oral Dissertation Defense, "Development of Small Molecule Inhibitors of Western Equine Encephalitis Virus Replication" Faculty Host: Scott Larsen ( [email protected] ) 615-0454
	September 25, 2014 4:00pm 2548 CC Little	Kim D. Janda, PhD Ely R. Callaway, Jr.; Professor of Chemistry; Director, Worm Institute for Research & Medicine (WIRM) The Scripps Research Institute Bacteria, Cancer, Addiction: Searching for Molecules that have Physiological Relevance Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Student Host: Erin Gallagher ( [email protected] ) Speaker Website
	October 2, 2014 4:00pm Palmer Commons, Forum Hall	John G. Topliss Lecture-William L. Jorgensen, PhD Sterling Professor of Chemistry;Director, Division of Physical Sciences & Engineering Yale University Efficient Lead Optimization Guided by Free-Energy Calculations Faculty Host: Heather Carlson ( [email protected] ) 615-6841 Speaker Website Speaker Abstract
	November 13, 2014 4:00pm 2548 CC Little	Peter Wipf, PhD Distinguished University Professor; Director of the Combinatorial Chemistry Center (CCC) and the Center for Chemical Methodologies and Library Development (UPCMLD) University of Pittsburgh, Department of Chemistry Chemical Inhibition of Protein Kinase D Faculty Host: Scott Larsen ( [email protected] ) 615-0454 Speaker Website Speaker Abstract
	December 1, 2014 10:00am Rackham Graduate School, East Conference Room	Xu Ran Medicinal Chemistry Ph.D. Candidate University of Michigan Oral Dissertation Defense "Peptide and nonpeptide approaches to target Protein-protein interactions for the treatment of cancer" Faculty Host: Shaomeng Wang ( [email protected] ) 615-0362
	January 6, 2015 4:00pm 2548 CC Little	Michael Van Nieuwenhze, PhD Associate Professor of Chemistry and Adjunct Professor of Microbiology, Molecular and Cellular Chemistry Indiana University Novel Chemical Probes for Use in the Study of Bacterial Peptidoglycan Biosynthesis Faculty Host: Hank Mosberg ( [email protected] ) 764-8117 Speaker Website
	January 15, 2015 4:00pm 2548 CC Little	Qing Lin, PhD Associate Professor Department of Chemistry, The State University of New York at Buffalo Opportunities at the Interface of Chemistry and Biology: A Bioorthogonal Chemistry Perspective Faculty Host: Hank Mosberg ( [email protected] ) 764-8117 Speaker Website
	January 20, 2015 4:00pm 2548 CC Little	Helen Waldschmidt Medicinal Chemistry, Third Year PhD Student University of Michigan Targeting G-protein coupled receptor kinase 2 as a potential heart therapeutic
	January 21, 2015 2:30-3:30pm 2548 CC Little	Emily Scott, PhD Associate Professor Department of Medicinal Chemistry, University of Kansas Structure/Function Studies of Human Steroidogenic Cytochrome P450 17A1: Improving Prostate Cancer Drug Design Faculty Host: Hank Mosberg ( [email protected] ) 764-8117 Speaker Website
	January 22, 2015 4:00pm 2548 CC Little	Mike Agius Medicinal Chemistry, Third Year PhD Student University of Michigan Development of Conformational Selective c-Src Inhibitors: Modulating the non-catalytic functions of c-Src Kinase
	January 27, 2015 4:00pm 2548 CC Little	Nate Scharf Medicinal Chemistry, Third Year PhD Student University of Michigan Development of in vitro Transcription Assay for Identification of Novel M. tuberculosis RNAP Inhibitors
	January 29, 2015 4:00pm 2548 CC Little	Eric Lachacz Medicinal Chemistry, Third Year PhD Student University of Michigan Profiled Kinase Inhibitors for Molecularly Targeting Sarcomas
	February 3, 2015 4:00pm 2548 CC Little	Megan Stewart Medicinal Chemistry, Third Year PhD Student University of Michigan Strategies for Green Fluorine-18 Radiochemistry & Dopamine D3 Receptor Radiotracer Discovery
	February 12, 2015 4:00pm 2548 CC Little	Joe Madak Medicinal Chemistry, Third Year PhD Student University of Michigan A Phenotypic Screen for the Development of New Therapeutics for Pancreatic Cancer
	February 17, 2015 4:00pm 2548 CC Little	Max Stefan Medicinal Chemistry, Third Year PhD Student University of Michigan Mycobacterium tuberculosis RNA polymerase: Compensatory Evolution and Therapeutic Development
	February 19, 2015 4:00pm 2548 CC Little	Isaac Krauss, PhD Assistant Professor of Chemistry Brandeis University Combining Organic Synthesis and Directed Evolution to Design HIV Carbohydrate Vaccine Candidates Faculty Host: Hank Mosberg ( [email protected] ) 764-8117 Speaker Website
	February 23, 2015 3:00pm 2548 CC Little	Douglas A. Hansen Medicinal Chemistry, Ph.D. Candidate University of Michigan PhD dissertation Defense: Type I Polyketide Synthases: Methodology, Biocatalysis, and Evaluation of Substrate Promiscuity Faculty Host: David Sherman ( [email protected] ) 615-9907
	February 24, 2015 4:00pm 2548 CC Little	Shasha Li Medicinal Chemistry, Third Year PhD Student University of Michigan Hapalindole-type Alkaloids from Cyanobacteria: Characterization of Biosynthetic Pathway for Drug Discovery
	February 26, 2015 10:00am Rackham Graduate School, East Conference Room	Kyle Heslip Medicinal Chemistry, Ph.D. Candidate University of Michigan PhD dissertation Defense: Inhibiting the Actions of Essential Biomolecule Phosphopantetheine Faculty Host: Ronald W. Woodard ( [email protected] ) 764-7366
	March 12, 2015 4:00pm 2548 CC Little	Craig Townsend, PhD Alsoph H. Corwin Professor of Chemistry Johns Hopkins University Biosynthesis of -Lactam Antibiotics and the Force of Convergent Evolution Faculty Host: Ron Woodard ( [email protected] ) 764-7366 Speaker Website Speaker Abstract
	March 17, 2015 4:00pm 2548 CC Little	Jennifer Schmidt Medicinal Chemistry, Third Year PhD Student University of Michigan Formation and evaluation of novel unit A cryptophycin analogues through the use of a thioesterase biocatalyst
	March 19, 2015 4:00pm 2548 CC Little	Michael Barbachyn, PhD Brummel Professor of Chemistry Calvin College Challenges in the Discovery of New Antibacterial Agents Faculty Host: Hollis Showalter ( [email protected] ) Speaker Website Speaker Abstract
	March 24, 2015 4:00pm 2548 CC Little	Will Kaplan Medicinal Chemistry, Third Year PhD Student University of Michigan Simple, Stereoselective, and Drug-oriented Synthesis of Steroids and their Polyoxygenated Derivatives
	March 26, 2015 4:00pm 2548 CC Little	Julie Boerner, PhD Assistant Professor, and Director of Chemical Biology Graduate Admissions Karmanos Cancer Institute/Department of Pharmacology, Wayne State University School of Medicine Src Family Kinases in Triple-Negative Breast Cancer Faculty Host: Matt Soellner ( [email protected] ) 615-2767 Speaker Website
	April 2, 2015 4:00pm 2548 CC Little	Alex Tropsha, PhD K.H. Lee Distinguished Professor and Associate Dean for Research University of North Carolina at Chapel Hill, Eshelman School of Pharmacy On the Importance of Data Curation in Molecular Modeling Faculty Host: Heather Carlson ( [email protected] ) 615-6841 Speaker Website
	April 9, 2015 4:00pm 2548 CC Little	Bryan Smith, PhD Senior Director of Biology Deciphera Pharmaceuticals; Lawrence, Kansas Kinase inhibitors targeting the tumor and tumor microenvironment Faculty Host: Matt Soellner ( [email protected] ) 615-2767 Speaker Website
	April 22, 2015 9:00am 2548 CC Little	Hao Xu Medicinal Chemistry, Ph.D. Candidate University of Michigan PhD Dissertation Defense: Profiling Ester Prodrugs Activation: an Activity Based Protein Profiling (ABPP) Approach Faculty Host: Gordon Amidon ( [email protected] ) 764-2464
	April 23, 2015 4:00pm 2548 CC Little	Leyte Winfield, PhD Associate Professor of Organic Chemistry and Chair, Department of Chemistry and Biochemistry Spelman College; Atlanta, Georgia Treatment Outcomes of LLW-3-6 in Prostate and Brain Cancer Cells Faculty Host: Ronald W. Woodard ( [email protected] ) 764-7366 Speaker Website
	May 14, 2015 11:00am 2548 CC Little	Anthony R. Porcari, PhD Director in Clinical Sciences Pfizer Tenth Annual Leroy B. Townsend Symposium: Recent advances in the treatment of venous thromboembolism: the role of new oral anticoagulants (NOACs) Faculty Host: Ronald W. Woodard 764-7366
	May 20, 2015 10:00am 2548 CC Little	Phani Ghanakota Medicinal Chemistry, Ph.D. Candidate University of Michigan PhD Dissertation Defense: Incorporating Hotspot Mapping and Allostery in Structure Based Drug Design Faculty Host: Heather Carlson ( [email protected] ) 615-6841
	June 11, 2015 4:00pm 1544 CC Little	Frederick T. Chin, Ph.D. Assistant Professor (Research) of Radiology (General Radiology); Stanford University Member, Molecular Imaging Program at Stanford Head, Cyclotron Radiochemistry Stanford University School of Medicine New Strategies for PET Imaging in Oncology and Neurology Faculty Host: Peter Scott ( [email protected] ) 615-1756 Student Host: Jason Miller ( [email protected] ) Speaker Website Speaker Abstract
	September 17, 2015 4:00pm 2548 CC Little	Shaomeng Wang, PhD Professor of Internal Medicine, Pharmacology, and Medicinal Chemistry University of Michigan Building a successful drug discovery program in Academia Faculty Host: Amanda Garner ( [email protected] ) Speaker Website
	October 15, 2015 4:00pm 2548 CC Little	Peter J. Scott, PhD Research Assistant Professor, Radiology University of Michigan New Strategies for Late-stage Fluorination and PET Imaging of Neurodegenerative Disorders Faculty Host: Amanda Garner ( [email protected] ) Speaker Website Speaker Abstract
	October 29, 2015 4:00pm Forum Hall, Fourth Floor, Palmer Commons	Christine Humblet, PhD Research Fellow Lilly Research Laboratories, Indianapolis, IN John G. Topliss Award Lecture: “Transforming drug discovery through predictive sciences. Computational Chemistry & Cheminformatics at Lilly” Faculty Host: Hollis Showalter ( [email protected] )
	November 5, 2015 4:00pm 2548 CC Little	Bill Wuest, PhD Assistant Professor Department of Chemistry, Temple University Draining the Moat: A Natural Product-Inspired Approach to Combat Bacterial Biofilms Faculty Host: David Sherman ( [email protected] ) 615-6907 Speaker Website Speaker Abstract
	November 12, 2015 4:00pm 2548 CC Little	Donna Huryn, PhD Research Professor, University of Pittsburgh, School of Pharmacy Adjunct Professor of Chemistry, University of Pennsylvania New Approaches to Modulating Protein Homeostasis in Cancer: Discovery and Optimization of Allosteric Inhibitors of p97 Faculty Host: George A. Garcia ( [email protected] ) 764-2202 Student Host: Andrea Shergalis ( [email protected] ) Speaker Website
	November 20, 2015 10:00am 4th Floor West Conference Room, Rackham	Anthony Emanuele Medicinal Chemistry, Ph.D. Candidate, PSTP Trainee University of Michigan PhD Dissertation Defense: Antibiotic Discovery Campaign Targeting VirF, the Main Transcriptional Regulator of Virulence in Shigella flexneri Faculty Host: George Garcia ( [email protected] ) 764-2202
	December 2, 2015 12:00pm 1706 Chemistry Building	Frank Kwarcinski Medicinal Chemistry Ph.D. Candidate University of Michigan PhD Dissertation Defense: Developing Kinase Inhibitors as Chemical Tools and Potential Drugs Faculty Host: Matt Soellner ( [email protected] ) 615-2767
	December 3, 2015 4:00pm 2548 CC Little	Kathleen A. Stringer, PhD Professor Clinical Pharmacy Department, College of Pharmacy, University of Michigan The Metabolomics of Drug Bioaccumulation in Macrophages: The Story of Clofazimine Faculty Host: Amanda Garner ( [email protected] ) Speaker Website Speaker Abstract
	January 7, 2016 10:00am Rackham Graduate School, West Conference Room (Fourth Floor)	Aubrie Harland Medicinal Chemistry, Ph.D. Candidate University of Michigan PhD Dissertation Defense, Design, Synthesis, and Optimization of Opioid Receptor Peptidomimetics Faculty Host: Henry I. Mosberg ( [email protected] ) 764-8117
	January 12, 2016 1:00pm 2548 CC Little	Aaron Bender Medicinal Chemistry, Ph.D. Candidate University of Michigan Ph.D. Dissertation Defense: Synthesis and Evaluation of Mixed Efficacy Mu Opioid Receptor (MOR), Delta Opioid Receptor (DOR) Small Molecule Ligands Faculty Host: Henry I. Mosberg ( [email protected] ) 764-8117
	January 19, 2016 4:00pm 2548 CC Little	Erin Gallagher Medicinal Chemistry, Ph.D. Candidate University of Michigan Third Year Student Seminar: Modulating the eIF4E-4E-BP Protein-Protein Interaction Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Abstract
	February 4, 2016 4:00pm 2548 CC Little	Yangbing Li Medicinal Chemistry, Ph.D. Candidate University of Michigan Third Year Student Seminar: Design of Selective BRM Bromodomain Inhibitors and Bivalent Small-Molecule Degraders of BRM for the Treatment of BRG1-Deficient Cancer Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Abstract
	February 9, 2016 4:00pm 2548 CC Little	Brandt Huddle Medicinal Chemistry, Ph.D. Candidate University of Michigan Third Year Student Seminar: Development of Ovarian Cancer Stem Cell Depleting ALDH Inhibitors Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Abstract
	February 11, 2016 4:00pm 2548 CC Little	Tony Nastase Medicinal Chemistry, Ph.D. Candidate University of Michigan Third Year Student Seminar: Design and Synthesis of Bifunctional Opioid Receptor Peptidomimetics Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Abstract
	February 18, 2016 4:00pm 2548 CC Little	Ting-Rong Chern Medicinal Chemistry, Ph.D. Candidate University of Michigan Third Year Student Seminar: Design, Synthesis and Characterization of Small Molecules Targeting MLL1 Methyltransferase in Mixed-Lineage Leukemia Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Abstract
	March 8, 2016 4:00pm 2548 CC Little	Allie Sowa Medicinal Chemistry, Ph.D. Candidate University of Michigan Third Year Student Seminar: Syntheses and Evaluation of GAT-1 Specific PET Probes Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Abstract
	March 10, 2016 4:00pm 2548 CC Little	Jeff Zwicker Medicinal Chemistry, Ph.D. Candidate University of Michigan Third Year Student Seminar: DEVELOPMENT OF SELECTIVE AND BRAIN PENETRANT INHIBITORS OF T. GONDII CATHEPSIN L Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Abstract
	March 17, 2016 4:00pm 2548 CC Little	Indraneel, Ghosh, PhD Associate Professor, Department of Chemistry and Biochemistry University of Arizona Split-Protein Engineering and Design: From Biosensors to Kinomics Faculty Host: Matt Soellner ( [email protected] ) 615-2767 Speaker Website Speaker Abstract
	March 24, 2016 4:00pm 2548 CC Little	Peter L. Toogood, PhD Senior Vice President, Chemistry and Chemical Biology Lycera Corporation Pharmaceutical Company Restoring Immune Balance Through Modulation of Metabolism and Cytokine Networks Faculty Host: Scott Larsen ( [email protected] ) 615-0454 Speaker Website
	April 8, 2016 9:00am Palmer Commons, Forum Hall, (fourth floor)	Denton Hoyer, PhD Director of Chemistry, Yale Center for Molecular Discovery Yale University Properties Matter: Pitfalls and Opportunities in Chemical Space Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Website
	May 19, 2016 2:00pm; Reception preceding lecture at 1:30 pm in room 2544 CC Little Building 2548 CC Little	Leah Makley, PhD; Eleventh Annual Leroy B. Townsend Symposium Chief Scientific Officer, Director; Viewpoint Therapeutics, San Francisco, California Development of a Medical Treatment for Cataract Based on a Pharmacological Chaperone of alpha-Crystallin Faculty Host: George A. Garcia ( [email protected] ) 734-764-2202 Speaker Website Speaker Abstract
	August 29, 2016 9:00am Life Sciences Institute Library, Room 3040	Michael F. Rafferty, Ph.D. Vice President of Preclinical Development Deciphera Pharmaceuticals, LLC. Medicinal Chemistry Education: Issues and Opportunities Faculty Host: Vincent E. Groppi, Ph.D. ( [email protected] ) Speaker Abstract
	September 14, 2016 10:00am Rackham Building, East Conference Room-Fourth Floor	Ahmed S. A. Mady Medcinal Chemistry, PhD Candidate University of Michigan Dissertation Defense: Development and characterization of novel Mcl-1 inhibitors for treatment of cancer Faculty Host: Zaneta Nikolvska-Coleska ( [email protected] ) 615-9202 Speaker Abstract
	September 15, 2016 4:00pm 2548 CC Little	Julio Camarero, PhD Associate Professor, Programs in Biomedical and Biological Sciences University of Southern California (USC) Cyclotides, a New Molecular Scaffold to Target Protein-Protein Interactions Faculty Host: Nouri Neamati ( [email protected] ) 647-2732 Speaker Website Speaker Abstract
	September 23, 2016 9:00am Rackham Amphitheater and Assembly Hall (Fourth Floor)	Amanda Garner, PhD Assistant Professor of Medicinal Chemistry University of Michigan Inaugural ACS MedChemSymposium: Chemical Approaches for Targeting Translational Control Student Host: Lindsey Drake ( [email protected] ) Speaker Website
	September 23, 2016 10:30am Rackham Amphitheater and Assembly Hall (Fourth Floor)	Emily Scott, PhD Associate Professor of Medicinal Chemistry and Associate Professor of Pharmacology University of Michigan Inaugural ACS MedChem Symposium: Cytochrome P450 17A1: Prostate Cancer Drug Target Student Host: Lindsey Drake ( [email protected] ) Speaker Website
	September 30, 2016 2:00pm 2548 CC Little	Zapporah Young Medicinal Chemistry, Ph.D. Candidate University of Michigan Dissertation Defense: Chemical Modulators of Heat Shock Protein 70 (Hsp70) Validate this Molecular Chaperone as a Target for Tauopathy Faculty Host: Scott Larsen ( [email protected] ) 615-0454
	October 20, 2016 4:00pm 2548 CC Little	Markos Koutmos Assistant Professor of Biochemistry and Molecular Biology Uniformed Services University of the Health Sciences RNA processing by mitochondrial RNase Ps; a new class of ribonucleases and their role in mitochondrial function Speaker Website
	October 21, 2016 10:00 am North Campus Research Complex (NCRC) Building 10, Research Auditorium	Parag Aggarwal, Ph.D. (UM-Medicinal Chemistry Alumni) Senior Program Officer, Addressing Disparities team Patient-Centered Outcomes Research Institute (PCORI) Research Funding at the Patient-Centered Outcomes Research Institute: Addressing Disparities Program Faculty Host: Stacey Trosell ( [email protected] ) Speaker Website
	October 27, 2016 4:00pm 2548 CC Little	Michelle Arkin, PhD Associate Professor, Department of Pharmaceutical Chemistry University of California, San Francisco (UCSF) Drug Discovery Challenges, Large and Small Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Website
	November 17, 2016 4:00pm Palmer Commons Forum Hall	Ruth Wexler, PhD Executive Director, Discovery Chemistry Bristol-Myers Squibb John G. Topliss Award Lecture- Adventures in Cardiovascular Drug Discovery: New Frontiers and Lessons Learned Faculty Host: Scott Larsen ( [email protected] ) 734-615-0454 Speaker Website Speaker Abstract
	November 24, 2016 n/a n/a	No Seminar-Thanksgiving Holiday N/A
	December 2, 2016 11:00am 1040 Dana Natural Resources Building	Taylor Johnson Medicinal Chemistry, Ph.D. Candidate University of Michigan Combining Active Site and Allosteric Inhibitors to Study Protein Tyrosine Kinases Faculty Host: Matt Soellner ( [email protected] ) 615-2767
	December 15, 2016 1:00pm Rackham Graduate School, West Conference Room (Fourth Floor)	Andrew C. Pratt Medicinal Chemistry PhD Candidate University of Michigan Oral Dissertation Defense: Functional analysis of early core region modification in the lipopolysaccharide of Gram-negative bacteria Faculty Host: Ronald Woodard ( [email protected] ) 764-7366
	January 12, 2017 4:00pm 2548 CC Little	Tim Cernak, PhD Associate Principal Scientist Merck and Co., Boston, MA Enabling Technologies in the Quest for New Medicines Faculty Host: Nouri Neamati ( [email protected] )
	January 17, 2017 4:00pm 2548 CC Little	Nathalie Busschaert, PhD Post-Doctoral Researcher New York University Supramolecular solutions to biomedical problems: From transmembrane anion transporters to protein-protein interaction inhibitors Faculty Host: Nouri Neamati ( [email protected] )
	January 17, 2017 4:00pm 2548 CC Little	Dennis Buckley, PhD Damon Runyan Postdoctoral Fellow Dana Farber Cancer Institute, Harvard Medical School Design of small molecule inducers of protein degradation, and their use as chemical probes Faculty Host: Nouri Neamati ( [email protected] )
	January 24, 2017 4:00pm 2548 CC Little	Megan Matthews, PhD Helen Hay Whitney Postdoctoral Fellow Department of Chemical Physiology, Scripps Research Institute Chemoproteomic profiling and discovery of protein electrophiles in human cells Faculty Host: Nouri Neamati ( [email protected] )
	January 31, 2017 4:00pm 2548 CC Little	Hubert Yin, PhD Associate Professor of Chemistry and Biochemistry University of Colorado at Boulder Drugging the Undruggable: Targeting Membrane Protein Interactions Faculty Host: Nouri Neamati ( [email protected] )
	February 7, 2017 4:00pm 2548 CC Little	Sumit Bandekar MedChem PhD Candidate, Third Year Student Seminar University of Michigan Structure, Function, and Inhibition of the Oncogenic RhoGEF TrioC Speaker Abstract
	February 14, 2017 4:00pm 2548 CC Little	Lindsey Drake MedChem PhD Candidate, Third Year Student Seminar University of Michigan Development of PET Probes for Biomarkers of Neuroinflammation Speaker Abstract
	February 16, 2017 4:00pm 2548 CC Little	Amy Fraley MedChem PhD Candidate, Third Year Student Seminar University of Michigan MalA: an iterative halogenase for late-stage C-H functionalization of indole alkaloids Speaker Abstract
	February 21, 2017 4:00pm 2548 CC Little	Ashootosh Tripathi, PhD Research Investigator Life Sciences Institute, University of Michigan Microbes to Medicine: Development of a Millennial Drug Discovery Platform Faculty Host: David Sherman ( [email protected] ) 615-9907 Speaker Abstract
	February 23, 2017 4:00pm 2548 CC Little	Shuai Hu MedChem PhD Candidate, Third Year Student Seminar University of Michigan Discovery of Novel Small-Molecule Reactive Oxygen Species (ROS) Inducers for Treating Pancreatic Cancer Speaker Abstract
	March 7, 2017 4:00pm 2548 CC Little	Christine Cuthbertson MedChem PhD Candidate, Third Year Student Seminar University of Michigan Discovery of First-in-Class SHMT2 and MTHFD2 Inhibitors for Non-Small Cell Lung Cancer Speaker Abstract
	March 9, 2017 4:00pm 2548 CC Little	Jeonghyo Lee MedChem PhD Candidate, Third Year Student Seminar University of Michigan Chiral phosphoric acids catalyzed regioselective and desymmetrizative glycosylation leading to the synthesis of aminoglycoside derivatives Speaker Abstract
	March 14, 2017 4:00pm 2548 CC Little	Nick Ragazzone MedChem PhD Candidate, Third Year Student Seminar University of Michigan Development of Novel Inhibitors Targeting VirF, the Key Virulence Regulator of Shigella flexneri Speaker Abstract
	March 16, 2017 4:00pm 2548 CC Little	Vikram Shenoy MedChem PhD Candidate, Third Year Student Seminar University of Michigan A novel fluorophosphonate probe for the identification of new valacyclovir-activating enzymes Speaker Abstract
	March 21, 2017 4:00pm 2548 CC Little	Andrea Shergalis MedChem Ph.D.Candidate, Third Year Student Seminar University of Michigan Preclinical evaluation of protein disulfide isomerase inhibitors for the treatment of glioblastoma Speaker Abstract
	March 23, 2017 4:00pm 2548 CC Little	Dylan Kahl MedChem PhD Candidate, Third Year Student Seminar University of Michigan Target Identification Studies for Two Novel Series of Rho-mediated Gene Transcription Inhibitors
	March 28, 2017 4:00pm 2548 CC Little	Sean Henry MedChem PhD Candidate, Third Year Student Seminar University of Michigan Development of Bifunctional Peptidomimetic Ligands as Novel Opioid Analgesics Speaker Abstract
	April 6, 2017 4:00pm 2548 CC Little	John K. Buolamwini, PhD Professor and Chair, Pharmaceutical Sciences Department, College of Pharmacy Rosalind Franklin University of Medicine and Science Design and Discovery of Potential Therapeutic Leads Targeted to Cancer, Heart and Viral Diseases
	May 1, 2017 10:00am Earl Lewis Room, Third Floor, Rackham Graduate School	David Cech PhD Candidate, Dissertation Defense Seminar University of Michigan, Department of Medicinal Chemistry Insights into the Mechanistic and Regulatory Properties of D-arabinose-5-phosphate Isomerases Faculty Host: Ronald Woodard ( [email protected] )
	May 3, 2017 10:00am 1706 Chemistry Building	Will P. Kaplan PhD Candidate, Dissertation Defense Seminar University of Michigan, Department of Medicinal Chemistry Drug-Oriented Synthesis of Cardiotonic Steroids Faculty Host: Pavel Nagorny ( [email protected] )
	May 18, 2017 2:00pm 2548 CC Little	Leroy B. Townsend Lectureship; Ji-Wang Chern, PhD, University of Michigan Alumnus, Medicinal Chemistry PhD, 1985 Distinguished Professor, School of Pharmacy; and Director, Center for Innovative Therapeutics Discovery, National Taiwan University Development of HDAC6 inhibitor as anticancer agent via autophagy inhibition and PD-L1 blockade Faculty Host: George A. Garcia ( [email protected] )
	May 25, 2017 2:00pm 2548 CC Little	Helen Waldschmidt PhD Candidate, Dissertation Defense Seminar University of Michigan, Department of Medicinal Chemistry Development, synthesis, and characterization of G protein-coupled receptor kinase inhibitors using structure based drug design for the advancement of heart failure therapeutics Faculty Host: Scott Larsen ( [email protected] )
	August 3, 2017 10:00am 2548 CC Little	Nathan Scharf PhD Candidate, Disseration Defense Seminar University of Michigan, Department of Medicinal Chemistry Identification and Evaluation of Bacterial RNA Polymerase Inhibitors Using a Novel Plasmid-based Transcription Assay Faculty Host: George A. Garcia ( [email protected] )
	August 17, 2017 10:00am 2548 CC Little Building	Michael Agius PhD Candidate, Dissertation Defense Seminar University of Michigan, Department of Medicinal Chemistry Modulating the Global Conformations of c-Src Kinase Faculty Host: Matt Soellner ( [email protected] )
	August 24, 2017 10:00am 2548 CC Little	Eric Lachacz PhD Candidate, Dissertation Defense Seminar University of Michigan, Department of Medicinal Chemistry Developing Target Identification Platforms Using Profiled Kinase Inhibitors Faculty Host: Matt Soellner ( [email protected] )
	September 21, 2017 4:00pm Forum Hall, Palmer Commons	Arun K. Ghosh, Ph.D. Ian P. Rothwell Distinguished Professor and Organic Division Chair Department of Chemistry & Department of Medicinal Chemistry, Purdue University John G. Topliss Award Lecture: Molecular Design Strategies to Combat HIV/AIDS Drug-resistance Faculty Host: Andy White ( [email protected] ) 647-7374 Speaker Website
	October 5, 2017 4:00pm 2548 CC Little	Deanna Montgomery MedChem Ph.D. Candidate University of Michigan Student Seminar: Design and Synthesis of Opioid Peptidomimetics for Treatment of Addiction Faculty Host: Hank Mosberg Speaker Abstract
	October 12, 2017 4:00pm 2548 CC Little	Jonathan Z. Sexton, PhD Associate Professor, Pharmaceutical Sciences; Director of Drug Discovery, BRITE North Carolina Central University Discovery and Development of Novel Activators of AMP-Activated Protein Kinase as Potential Therapeutics for Fatty Liver Disease and NASH Speaker Website Speaker Abstract
	November 2, 2017 4:00pm 2548 CC Little	Jason K. Sello, PhD Associate Professor of Chemistry Department of Chemistry, Brown University; Providence, Rhode Island Novel Small Molecules, Targets, and Strategies in Anti-Infective Development Faculty Host: George Garcia ( [email protected] ) 764-2022 Student Host: Nick Ragazzone ( [email protected] ) Speaker Website
	November 6, 2017 10:00am Rackham Graduate School, Earl Lewis Room, Third Floor	Shasha Li PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Decoding the Bio-assembly of Hapalindole-type Alkaloids from Cyanobacteria for Drug Discovery Faculty Host: David Sherman ( [email protected] ) 615-9907
	November 16, 2017 4:00pm 2548 CC Little	Roger D. Cone, PhD Vice Provost and Director of the Biosciences Initiative; Asa Gray Collegiate Professor of the Life Sciences, Mary Sue Coleman Director of the Life Sciences Institute; Professor of Molecular, Cellular and Developmental Biology, and Professor of Molecular and Integrative Physiology, University of Michigan Allosteric Modulators of the Melanocortin-4 Receptor Faculty Host: Emily Scott ( [email protected] ) 764-3530 Student Host: Sarah Burris Speaker Website
	November 30, 2017 4:00pm 2548 CC Little	John Montgomery, PhD Margaret and Herman Sokol Professor in Medicinal or Synthetic Chemistry Department of Chemistry, University of Michigan Development of New Catalytic Reactions for Late-Stage Diversification Faculty Host: David Sherman ( [email protected] ) 615-9907 Speaker Website
	December 7, 2017 1:00pm Location To Be Announced	Megan Stewart PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Positron Emission Tomography Radiochemistry: Improved Methodology and a Novel PET Imaging Agent for the Dopamine D3 Receptor Faculty Host: Peter J. Scott ( [email protected] ) 615-1756
	December 7, 2017 4:00pm 2548 CC Little	Yoichi Osawa, Ph.D. Warner-Lambert/Parke-Davis Professor in Medicine Department of Pharmacology, University of Michigan Surveillance of Protein Clefts by Chaperones in Protein Quality Control: Rationale for a New Approach in Treatment of Protein Folding Diseases Faculty Host: Emily Scott ( [email protected] ) 764-3530 Speaker Website
	January 17, 2018 1:00pm NCRC Building 10, Research Auditorium	Joseph Madak PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Design and Synthesis of Novel Dihydroorotate Dehydrogenase Inhibitors Faculty Host: Nouri Neamati ( [email protected] ) 647-2732
	January 18, 2018 4:00pm 2548 CC Little	Melanie D. Ohi, PhD Associate Professor; Research Associate Professor, Life Sciences Institute Medical School, Cell and Developmental Biology; University of Michigan Structural analysis of dynamic molecular machines using cryo-electron microscopy Faculty Host: Amanda Garner Speaker Website
	January 23, 2018 4:00pm 2548 CC Little	Maria Fawaz PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry, University of Michigan MedChem Student Seminar: Synthetic HDL Lipid Scavengers for the Treatment of Niemann-Pick Diseases Faculty Host: Anna Schwendeman ( [email protected] ) Speaker Abstract
	January 25, 2018 4:00pm 2548 CC Little	Andrei Lomize, PhD Research Scientist Department of Medicinal Chemistry, University of Michigan Developments of computational tools and databases to study proteins and drugs in membranes Faculty Host: Henry I. Mosberg ( [email protected] ) Speaker Website
	February 6, 2018 4:00pm 2548 CC Little	Shireen Ashkar PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry, University of Michigan Development of Novel Inhibitors for Rifamycin-resistant RNA Polymerase of Mycobacterium tuberculosis Faculty Host: George A. Garcia ( [email protected] ) Speaker Abstract
	February 8, 2018 4:00pm 2548 CC Little	Brandon Ruotolo Associate Professor Department of Chemistry, University of Michigan Gas-phase Structural Biology: New Technologies for Rapidly Assessing Protein Complex Sequence, Structure and Stability Faculty Host: David Sherman ( [email protected] ) 615-9907 Speaker Website Speaker Abstract
	February 13, 2018 4:00pm 2548 CC Little	Katherine Guild PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry, University of Michigan Investigation of Mycobacterium tuberculosis RNA Polymerase for the Development of Novel Drug Candidates Faculty Host: George A. Garcia ( [email protected] ) Speaker Abstract
	February 22, 2018 4:00pm 2548 CC Little	Rachel Rowlands PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry, University of Michigan Development of Selective, Covalent Inhibitors of GRK5 for Treatment of Heart Failure Faculty Host: Andy White ( [email protected] ) Speaker Abstract
	March 8, 2018 4:00pm 2548 CC Little	Yongcheng Song, PhD Associate Professor, Pharmacology and Chemical Biology Baylor University, Baylor College of Medicine; Houston, TX Small Molecule Probes Targeting Histone Methylation for Cancer Therapy Faculty Host: Shaomeng Wang ( [email protected] ) 615-0362 Speaker Website
	March 22, 2018 4:00pm 2548 CC Little	Bob Kennedy, PhD Interim President and CEO Vestaron Corporation; Kalamazoo, MI Venom Peptides in Drug Design and as Novel Insecticides Faculty Host: Scott D. Larsen ( [email protected] ) 615-0454 Speaker Website Speaker Abstract
	April 5, 2018 4:00pm 2548 CC Little	Matt Bogyo, PhD Professor of Pathology and of Microbiology and Immunology Stanford University Chemical probes for imaging and therapeutic applications in cancer and infectious disease Faculty Host: Amanda Garner ( [email protected] ) 763-654 Speaker Website
	April 12, 2018 4:00pm 2548 CC Little	Terry Moore, PhD Medicinal Chemistry and Pharmacognosy College of Pharmacy, University of Illinois Development of Chemical Probes for Transcription Factor Interactions Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Website
	May 17, 2018 2:00pm 1544 NUB	Leroy B. Townsend Award Lectureship; Yousong Ding, PhD, University of Michigan Alumnus, Medicinal Chemistry PhD, 2010 Assistant Professor of Medicinal Chemistry University of Florida, Gainesville, FL Exploiting Microbial Genomes to Access New Enzymology and Valuable Chemicals Faculty Host: George A. Garcia ( [email protected] ) 764-2202 Speaker Website Speaker Abstract
	May 17, 2018 2:00pm 1544 NUB	Leroy B. Townsend Award Lectureship; Yousong Ding, PhD, University of Michigan Alumnus, Medicinal Chemistry PhD, 2010 Assistant Professor of Medicinal Chemistry University of Florida; Gainesville, FL Exploiting Microbial Genomes to Access New Enzymology and Valuable Chemicals Faculty Host: George Garcia ( [email protected] ) 764-2202 Speaker Website Speaker Abstract
	May 18, 2018 8:30am Rackham Amphitheater and Assembly Hall, Fourth Floor	ACS MedChem Student Chapter Career Forum with Keynote Speaker: Bruce Roth, PhD Former Senior Vice President of Small Molecule Drug Discovery, and Co-Leader of Genentech Research Genentech, Inc. The Discovery and Development of Lipitor: Would Anyone Make This Molecule Today? Faculty Host: ACS MedChem Student Chapter ( [email protected] ) Student Host: Nicholas Ragazzone and Andrea Shergalis Speaker Website Speaker Abstract
	May 31, 2018 1:00pm 2548 NUB	Maxwell A. Stefan PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Kinetic Characterization of Rifamycin-Resistant M. tuberculosis RNA polymerases and Novel Therapeutic Approach for Targeting Transcription Faculty Host: Geogre A. Garcia ( [email protected] ) Speaker Abstract
	June 8, 2018 9:30am 2548 NUB	Yangbing Li PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Development of novel PROTAC Small-Molecule Degraders of MDM2 Protein and Peptidomimetic Inhibitors Targeting WDR5-MLL1 Protein-Protein Interaction Faculty Host: Shaomeng Wang ( [email protected] ) 615-0362 Speaker Abstract
	July 27, 2018 1:00pm 1544 NUB	Jordan Clark PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Structural Investigation of Binding Events in Proteins Faculty Host: Heather Carlson ( [email protected] ) 615-6841
	August 16, 2018 2:00pm 1544 NUB	Brandt C. Huddle PhD Candidate, Dissertation Defense Seminar University of Michigan, Department of Medicinal Chemistry Development of Cancer-Stem-Cell Targeting Pan-Aldehyde Dehydrogenase Inhibitors as an Adjunct to Chemotherapy in the Treatment of Ovarian Cancer Faculty Host: Scott Larsen ( [email protected] ) 615-0454
	August 20, 2018 10:00am 2548 NUB	Jeffery Zwicker PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Development of CNS Penetrant Inhibitors of Toxoplasma gondii Cathepsin L Faculty Host: Scott Larsen
	August 28, 2018 1:00pm Palmer Commons, Forum Hall	Jennifer J. Schmidt PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Chemoenzymatic Assembly of Macrolactones: Merging Synthetic Chemistry with Biocatalysis to Afford Diverse Compound Libraries Faculty Host: David Sherman ( [email protected] ) 615-9907
	August 29, 2018 2:00pm Rackham Graduate School, Earl Lewis Room	Alexandra Sowa PhD Candidate, Dissertation Defense Seminar University of Michigan, Department of Medicinal Chemistry Synthesis and Evaluation of GAT-1 Selective Probes for Positron Emission Tomography Faculty Host: Peter J H Scott ( [email protected] ) 615-1756
	September 13, 2018 4:00pm 2548 NUB	James C. Barrow, Ph.D. Associate Director, Drug Discovery and Associate Professor Lieber Institute for Brain Development and Johns Hopkins School of Medicine Discovery and evaluation of non-nitrocatechol COMT inhibitors for treatment of psychiatric conditions Faculty Host: Shaomeng Wang ( [email protected] ) 615-0362 Speaker Website Speaker Abstract
	September 20, 2018 4:00pm 2548 NUB	Amanda L. Garner, Ph.D. Assistant Professor, Department of Medicinal Chemistry University of Michigan Chemical Probing of Translational Control and microRNA Biology Faculty Host: George Garcia Speaker Website
	September 27, 2018 4:00pm 2548 NUB	Jason Kwan, PhD Assistant Professor, Pharmaceutical Sciences Division School of Pharmacy, University of Wisconsin, Madison Exploring the biosynthetic potential of uncultured microbes Faculty Host: David Sherman ( [email protected] ) 615-9907 Speaker Website Speaker Abstract
	October 4, 2018 4:00pm Forum Hall, Palmer Commons	John G. Topliss Award Lecture, Ann E. Weber, Ph.D. Senior Vice President - Drug Discovery Kallyope Inc., New York, NY From JANUVIA to MARIZEV (Omarigliptin), a Once Weekly DPP-4 Inhibitor for the Treatment of Diabetes Faculty Host: Scott Larsen ( [email protected] ) 615-0454 Speaker Abstract
	October 5, 2018 2:30pm Palmer Commons, Forum Hall	Anthony Nastase PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan The Design, Synthesis, and Pharmacological Evaluation of Bifunctional Mu-/Delta-Selective Opioid Receptor Ligands for the Treatment of Pain Faculty Host: Henry Mosberg ( [email protected] ) 764.8117
	October 11, 2018 4:00pm 2548 NUB	John A. Porco, Jr., Ph.D. CMD Director and Professor of Chemistry Department of Chemistry and Center for Molecular Discovery (BU-CMD),Boston University Recent Studies Towards the Synthesis of Bioactive Natural Products Faculty Host: Tim Cernak ( [email protected] ) 647-6793 Speaker Website
	October 25, 2018 4:00pm 2548 NUB	Stephen Husbands, Ph.D. Professor, Department of Pharmacy and Pharmacology; Centre for Therapeutic Innovation University of Bath, United Kingdom Solving the Opioid Crisis - with Opioids Faculty Host: John R. Traynor and Hank Mosberg ( [email protected] ) 647-7479 Speaker Website
	November 1, 2018 4:00pm 2548 NUB	Jason M. Crawford, Ph.D. Maxine F. Singer '57 Ph.D. Associate Professor of Chemistry and Associate Professor of Microbial Pathogenesis Yale University; New Haven, CT Chemistry at the Host-Bacteria Interface Faculty Host: David Sherman ( [email protected] ) 615-9907 Speaker Website
	November 8, 2018 4:00pm 2548 NUB	Eugene Chen, PhD Frederick G L Huetwell Professor of Cardiovascular Medicine, Professor of Internal Medicine, Professor of Surgery, Professor of Pharmacology, and Professor of Molecular and Integrative Physiology Medical School, University of Michigan Nitration of unsaturated fatty acids: from bench to bedside Faculty Host: George Garcia ( [email protected] ) 764-2202 Speaker Website
	November 13, 2018 10:30am Fourth Floor, Palmer Commons	Third Annual ACS Medicinal Chemistry Symposium Tom Poulos, Ph. D., University of California, Irvine; and Ann E. Weber, Kallyope Inc. New York, NY Full Day Symposium Full schedule to be announced Faculty Host: ACS MEDI Graduate Student Chapter Speaker Website Speaker Abstract
	December 12, 2018 10:00am 1544 NUB	Dylan Kahl PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Advancement of Two Novel Series of Rho-mediated Gene Transcription Inhibitors with Anti-Fibrotic Properties Faculty Host: Scott Larsen ( [email protected] ) 615-0454
	December 13, 2018 2:00pm 1544 NUB	Erin Gallagher PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Modulating the eIF4E-eIF4G Protein-Protein Interaction Faculty Host: Amanda L. Garner ( [email protected] ) 763-2654
	January 8, 2019 2:00pm Forum Hall, Palmer Commons, Fourth Floor	Roland Kersten, PhD Post-Doctoral Associate, Whitehead Institute for Biomedical Research Massachusetts Institute of Technology (MIT), Cambridge, MA Genomics-guided discovery of peptide natural products in microbes and plants Faculty Host: TIm Cernak ( [email protected] ) 647-6793 Speaker Website Speaker Abstract
	January 24, 2019 4:00pm 2548 NUB	Sean Tanzey PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry, University of Michigan Third Year Student Seminar: Synthesis and Evaluation of Metal-Specific Chelating Radioligands Faculty Host: Peter Scott ( [email protected] ) 615-1756 Speaker Abstract
	February 7, 2019 4:00pm 2548 NUB	Maha Zidan, M.Sc. PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry, University of Michigan Third Year Student Seminar: Targeting STAT3 Signaling as a Therapeutic Approach for Cancer Treatment Faculty Host: Nouri Neamati ( [email protected] ) Speaker Abstract
	February 21, 2019 4:00pm 2548 NUB	Atsunori Kaneshige PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry, University of Michigan Third Year Student Seminar: Development of Small-Molecule STAT6 Degraders Faculty Host: Shaomeng Wang ( [email protected] ) 615-0362 Speaker Abstract
	March 5, 2019 10:00am Rackham West Conference Room, 4th Floor	Lindsey R. Drake PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan PET Imaging of Novel Biomarkers of Neuroinflammation Faculty Host: Peter JH Scott ( [email protected] ) 615-1756 Speaker Abstract
	March 14, 2019 4:00pm 2548 NUB	Tomi K. Sawyer, PhD Distinguished Scientist, Discovery Chemistry Modalities & Peptide Drug Hunter Merck Research Laboratories, Boston, MA Macrocyclic Peptide Antagonists of MDM2 and MDMX: Drug Design and Cell Permeability Faculty Host: Henry I. Mosberg ( [email protected] ) 764-8117 Speaker Website
	March 21, 2019 4:00pm 2548 NUB	Alison Narayan, PhD William R. Roush Assistant Professor, Research Assistant Professor, and Assistant Professor Department of Chemistry, and Life Sciences Institute; University of Michigan Biocatalysis and complex molecule synthesis Faculty Host: Heather Carlson ( [email protected] ) 615-6841 Speaker Website
	March 25, 2019 4:00pm 1544 NUB	Jeonghyo Lee PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Chiral phosphoric acid catalyzed regioselective functionalization of carbohydrates Faculty Host: Pavel Nagorny ( [email protected] ) 615-2833
	April 4, 2019 4:00pm 2548 NUB	Michelle James, PhD Assistant Professor of Radiology and Neurology & Neurological Sciences Molecular Imaging Program at Stanford (MIPS) University, School of Medicine Developing Novel PET Tracers for Imaging Neuroimmune Interactions in CNS diseases Speaker Website
	April 11, 2019 4:00pm 2548 NUB	Bradley S. Moore, PhD Professor, Skaggs School of Pharmacy and Pharmaceutical Sciences, and Scripps Institution of Oceanography University of San Diego Connecting genes to chemistry to empower small molecule discovery Faculty Host: David H. Sherman ( [email protected] ) 615-9907 Speaker Website
	May 9, 2019 2:00pm 1544 NUB	Leroy B. Townsend Award Lectureship; Timothy C. Meredith, PhD University of Michigan Alumnus, Medicinal Chemistry PhD, 2006 Assistant Professor of Biochemistry and Molecular Biology, Penn State University Strategies for antimicrobial discovery....and why we need to keep looking Faculty Host: George A. Garcia ( [email protected] ) 734-764-2202 Speaker Website
	May 16, 2019 10:00am 1200 Chemistry Building	Reinventing Drug Discovery through Chemical Biology Multiple Speakers Faculty Host: Amanda Garner Speaker Website
	May 31, 2019 10:00am Forum Hall, Palmer Commons	Amy E. Fraley PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Molecular Basis for Selective Late-Stage Transformations in Fungal Indole Alkaloid Biosynthesis Faculty Host: David Sherman ( [email protected] ) 615-9907
	July 19, 2019 2:00pm Rackham Graduate School: East Conference Room, fourth floor	Deanna Montgomery PhD Candidate, Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Design, Synthesis, and Evaluation of Novel, Multifunctional Dimethyltyrosine-Tetrahydroisoquinoline Opioid Peptidomimetics Faculty Host: Henry I. Mosberg ( [email protected] ) 764-8117
	September 9, 2019 3:00pm 1567 NUB	Ting-Rong Chern PhD Candidate, Oral Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Design and Synthesis of Potent Small-Molecule Inhibitors of MLL-1 Methyltransferase and Selective Inhibitors of the DCN Protein Families Faculty Host: Shaomeng Wang ( [email protected] ) 615-0362
	September 26, 2019 4:00pm 2548 NUB	Edward Yu, PhD Professor, Department of Pharmacology Medical School, Case Western Reserve University Fighting Superbugs Faculty Host: Emily Scott ( [email protected] ) 764-3530 Student Host: Sarah Burris ( [email protected] ) Speaker Website Speaker Abstract
	October 1, 2019 2:00pm Palmer Commons, Forum Hall (Fourth Floor)	Sean Henry PhD Candidate, Oral Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Structural Evolution of a Bifunctional Mu-Opioid Receptor (MOR)/Delta-Opioid Receptor (DOR) Peptidomimetic Faculty Host: Henry I. Mosberg ( [email protected] ) 764-8117
	October 3, 2019 4:00pm 2548 NUB	Patrick O'Brien, PhD Associate Professor, Biological Chemistry University of Michigan Chemistry & Biology of Human DNA Ligases Faculty Host: Amanda L. Garner ( [email protected] ) 763-2654 Speaker Website
	October 24, 2019 4:00pm 2548 NUB	Angelo Aguilar, PhD Assistant Research Scientist Internal Medicine, Hematology and Oncology, University of Michigan Discovery of APG-115 an MDM2 Inhibitor in Clinical Trials and AA-265 a PROTAC MDM2 Degrader Clinical Candidate Faculty Host: Amanda Garner ( [email protected] ) 763-2654
	October 29, 2019 2:30pm 2548 NUB	John Katzenellenbogen, PhD Professor, Department of Chemistry University of Illinois at Urbana-Champaign Understanding—and Overcoming—Therapy Resistance in Breast and Prostate Cancerss Faculty Host: Peter Scott ( [email protected] ) 615-1756 Speaker Website
	October 31, 2019 4:00pm 2548 NUB	Laura M. Sanchez, PhD Assistant Professor Pharmaceutical Sciences, University of Illinois at Chicago Visualizing Microbial and Cellular Chemistry in Situ Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Website
	November 7, 2019 4:00pm 2548 NUB	Ryoma Ohi, PhD Associate Professor of Cell & Developmental Biology, and Adjunct Research Associate Professor, Life Sciences Institute University of Michigan Trimming the C-Terminal Tail of Alpha-tubulin: What is it good for? Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Website
	November 14, 2019 4:00pm 2548 NUB	Amanda E. Hargrove, PhD Assistant Professor of Chemistry and Biochemistry Duke University, Trinity College of Science and the Arts, Durham, NC From Patterns to Function in Small Molecule: RNA Interactions Faculty Host: Tim Cernak ( [email protected] ) 647-6793 Speaker Website
	December 6, 2019 11:00am NCRC Building 300, Room 376	Andrea Shergalis PhD Candidate, Oral Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Preclinical Evaluation of Protein Disulfide Isomerase Inhibitors for the Treatment of Glioblastoma Faculty Host: Nouri Neamati ( [email protected] ) 647-2732
	December 9, 2019 3:00pm 3040 Life Sciences Institute (Library)	Sumit J. Bandekar PhD Candidate, Oral Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Structure and Function of the Oncogenic RhoGEF Trio Faculty Host: Janet Smith ( [email protected] ) 615-9564
	January 9, 2020 10:00am 2548 NUB	Vikram P. Shenoy PhD Candidate, Oral Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan A Proteomic Approach to Identification of Prodrug-Activating Serine Hydrolases: Activation of Valacyclovir Faculty Host: Gordon Amidon
	January 13, 2020 2:00pm NCRC Building 10, Room G065	Maria V. Fawaz PhD Candidate, Oral Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Apolipoprotein A-I Mimetics for the Treatment of Niemann-Pick Disease Faculty Host: Anna Schwendeman ( [email protected] ) 763-4056
	January 16, 2020 4:00pm 2548 NUB	Jake Hitchens PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry, University of Michigan Exploration of Novel, CNS Penetrant Inhibitors of T. Gondii Cathepsin L Faculty Host: Andy White ( [email protected] ) 647-7374 Speaker Abstract
	January 28, 2020 4:00pm 2548 NUB	Rachel Torrez PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry Structural and functional analysis of human DICER1 Faculty Host: Amanda Garner ( [email protected] ) 763-2654 Speaker Abstract
	January 30, 2020 4:00pm 2548 NUB	Garrett Dow PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry, University of Michigan Targeting VirF, the Master Transcriptional Activator of Virulence in Shigella flexneri, as a novel route to treat Shigellosis Faculty Host: George A. Garcia ( [email protected] ) 764.2202 Speaker Abstract
	February 11, 2020 10:00am Rackham Graduate School, West Conference Room	Rachel Rowlands PhD Candidate, Oral Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Expanding the Arsenal: Development of G Protein-Coupled Receptor Kinase 5 Inhibitors Utilizing a Covalent Strategy Faculty Host: Andy White ( [email protected] ) 647-7374
	February 13, 2020 4:00pm 2548 NUB	Robbie Hohlman PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry, University of Michigan Exploration of Stig Cyclases as Biocatalytic Tools for Unnatural Indole Alkaloid Production Faculty Host: David Sherman ( [email protected] ) 615-9907 Speaker Abstract
	February 18, 2020 4:00pm 2548 NUB	Yuning Shen PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry, University of Michigan Novel Transformation Development of Acid–Amine Coupling Facilitated by Ultra-high Throughput Experimentation Faculty Host: Tim Cernak ( [email protected] ) 647-6793 Speaker Abstract
	February 25, 2020 4:00pm 2548 NUB	Peter L. Toogood, PhD Michigan Drug Discovery (MDD) Director, Life Sciences Institute; and Adjunct Professor of Medicinal Chemistry College of Pharmacy, University of Michigan Small Molecule Immuno-Oncology Therapeutic Agents: RORγ Agonists for Treating Cancer Faculty Host: Scott Larsen ( [email protected] )
	February 27, 2020 4:00pm 2548 NUB	Glory Velazquez PhD Candidate, MedChem Student Seminar Department of Medicinal Chemistry, University of Michigan Antibiotic Discovery of Inhibitors of the CarD-RNA Polymerase Protein-Protein Interaction in Mycobacterium tuberculosis Faculty Host: George Garcia ( [email protected] ) 764-2202 Speaker Abstract
	March 12, 2020 4:00pm 2548 NUB	Jeffrey Aube, PhD Fred Eshelman Distinguished Professor, Division of Chemical Biology and Medicinal Chemistry School of Pharmacy, University of North Carolina at Chapel Hill Revisiting Old Problems in Infectious Disease and Organic Chemistry Faculty Host: Tim Cernak ( [email protected] ) 647-6793 Speaker Website
	May 13, 2020 2:00pm BLUEJEANS.COM/ 287068993	Shuai Hu PhD Candidate, Oral Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Discovery and Mechanistic Studies of Novel Redox Modulators for Treatment of Pancreatic Cancer Faculty Host: Nouri Neamati, PhD ( [email protected] ) Speaker Abstract
	October 8, 2020 4:00pm Zoom Remote	Darci J. Trader, PhD Assistant Professor of Medicinal Chemistry and Molecular Pharmacology Purdue University; West Lafayette, IN Methods to Evaluate and Perturb the Activity of the Human Proteasome with Small Molecules Faculty Host: Prof. Amanda L. Garner, PhD ( [email protected] ) Student Host: Rachel Torrez ( [email protected] ) Speaker Website Speaker Abstract
	October 15, 2020 4:00pm Zoom Remote	Hosein Mohimani, PhD Assistant Professor, Computational Biology Department, School of Computer Science Carnegie Mellon University; Pittsburgh, PA Computational methods for small molecule natural product discovery Faculty Host: Prof. Roland Kersten ( [email protected] ) Speaker Website Speaker Abstract
	October 22, 2020 4:00pm Zoom Remote	Jennifer C. Petter, PhD Founder and Chief Scientific Officer Arrakis Therapeutics; Waltham MA Drugging RNA Structures with Small Molecules Faculty Host: Prof. Amanda L. Garner, PhD ( [email protected] ) Speaker Website Speaker Abstract
	November 5, 2020 4:00pm Zoom Remote	Simone Brixius-Anderko, PhD Research Fellow, Department of Medicinal Chemistry College of Pharmacy, University of Michigan; Ann Arbor, MI Understanding Aldosterone Biosynthesis for Enhanced Treatment of Hypertension Faculty Host: Prof. Amanda L. Garner, PhD ( [email protected] ) Speaker Website Speaker Abstract
	November 12, 2020 4:00pm Zoom Remote	Alessandra S. Eustaquio, PhD Assistant Professor, Department of Medicinal Chemistry and Pharmacognosy and Center for Pharmaceutical Biotechnology College of Pharmacy, University of Illinois, Chicago (UIC) From DNA to natural products through genetics Faculty Host: Prof. Amanda L. Garner, PhD ( [email protected] ) Speaker Website Speaker Abstract
	December 4, 2020 3:00pm Zoom	Christine Cuthbertson PhD Candidate, Oral Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Inhibition of Nucleotide and One-Carbon Metabolism for the Treatment of Cancer Faculty Host: Nouri Neamati ( [email protected] ) Speaker Abstract
	December 14, 2020 12:00pm Zoom	Sean Tanzey PhD Candidate, Oral Dissertation Defense Seminar Department of Medicinal Chemistry, University of Michigan Novel Approaches to PET Imaging Neurodegeneration Faculty Host: Peter JH Scott ( [email protected] ) Speaker Abstract
Seminar Link	January 26, 2021 4:00pm Zoom Virtual Seminar Link	Luis Cervantes Medicinal Chemistry Candidate, Third-Year Student Seminar College of Pharmacy, Univeristy of Michigan Large Scale Prediction of Relative Free Energies of Ligand Binding Using Multi-Site Lambda Dynamics (MSLD) Faculty Host: Charles L. Brooks, III ( [email protected] ) Speaker Abstract
Seminar Link	January 28, 2021 4:00pm Zoom Virtual Seminar Link	Troy Halseth Medicinal Chemistry PhD Candidate; Third-Year Student Seminar College of Pharmacy, University of Michigan Apolipoprotein-Mimetics for the Treatment of Niemann-Pick Diseases Faculty Host: Anna Schwendeman ( [email protected] ) Speaker Abstract
Seminar Link	February 2, 2021 4:00pm Zoom Virtual Seminar Link	Jinghan Liu Medicinal Chemistry PhD Candidate; Third-Year Student Seminar College of Pharmacy, University of Michigan Structure and Function of Human Cytochrome P450 8B1 Faculty Host: Emily Scott ( [email protected] ) Speaker Abstract
	February 9, 2021 4:00pm Zoom virtual	Sean McCarty Medicinal Chemistry PhD Candidate; Third-Year Student Seminar College of Pharmacy, University of Michigan Identification and Development of Novel Scaffolds for ꞵ-Cell Proliferation Faculty Host: Jonathan Sexton ( [email protected] ) Speaker Abstract
Seminar Link	February 11, 2021 4:00pm Zoom Virtual Seminar Link	Andrew McGrath Medicinal Chemistry PhD Candidate; Third-Year Student Seminar College of Pharmacy, University of Michigan Nontraditional Amine-Acid Coupling Reactions to Explore Structure-Function Relationships Faculty Host: Tim Cernak ( [email protected] ) Speaker Abstract
Seminar Link	February 16, 2021 4:00pm Zoom Virtual Seminar Link	Ryan Rutkoski Medicinal Chemistry PhD Candidate; Third-Year Student Seminar College of Pharmacy, University of Michigan Development of Solid Supported Glycosyl Donors for the Glycosylation of Natural Products Faculty Host: Pavel Nagorny ( [email protected] ) Speaker Abstract
	February 25, 2021 4:00pm Zoom Virtual	Jesse Wotring Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Accelerated Compound Repurposing Using High Content Imaging: Application to Non-Alcoholic Fatty Liver Disease Faculty Host: Jonathan Sexton ( [email protected] ) Speaker Abstract
Seminar Link	March 4, 2021 4:00pm Zoom Virtual Seminar Link	Sherrice Zhang Medicinal Chemistry PhD Candidate; Third-Year Student Seminar College of Pharmacy, University of Michigan Development of δ-Opioid Receptor (DOR) Positive Allosteric Modulators (PAMs) for the Treatment of Depression Faculty Host: Andy White ( [email protected] ) Speaker Abstract
Seminar Link	March 9, 2021 4:00pm Zoom Virtual Seminar Link	Yihao Zhuang Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Discovery of Novel Natural Products that Inhibit eIF4E Protein-Protein Interactions Faculty Host: Amanda Garner ( [email protected] ) Speaker Abstract
Seminar Link	March 18, 2021 4:00pm Zoom Virtual Seminar Link	Wenbin Tu Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Development of PROTAC degraders of SMARCA proteins for the treatment of cancer Faculty Host: Shaomeng Wang [email protected] Speaker Abstract
Oral Defense Link	March 19, 2021 1:00pm Zoom Remote Oral Defense Link	Maha Hanafi PhD Candidate, Department of Medicinal Chemistry University of Michigan, Oral Dissertation Defense Targeting Sigma-2 Receptor and ZFP91 in Pancreatic Cancer Faculty Host: Nouri Neamati ( [email protected] ) Speaker Abstract
Seminar Link	March 25, 2021 4:00pm Zoom Virtual Seminar Link	Charles Zhang Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Human Liver Organoids to Assess Idiosyncratic Drug-Induced Liver Injury Faculty Host: Jonathan Sexton ( [email protected] ) Speaker Abstract
Seminar Link	April 8, 2021 4:00pm Zoom Remote Seminar Link	Rebecca T. Ruck, PhD Executive Director of Enabling Technologies, Small Molecule PR&D Merck Research Laboratories, Process Research & Development Enabling Technologies for the green synthesis of Pharmaceutical Agents at Merck Speaker Website Speaker Abstract
Seminar Link:	April 15, 2021 4:00pm Zoom Remote: Seminar Link:	Maud Reiter, PhD Director of New & Renewable Ingredients, Research & Development Division Firmenich S.A. in Geneva (Switzerland) Firmenich’s quest towards sustainable muguet molecules Faculty Host: Tim Cernak ( [email protected] ) Speaker Website Speaker Abstract
Zoom link	January 6, 2022 4:00pm Virtual Zoom link	Bo Mahjour Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Accelerating the discovery and invention of critical chemical transformations via Systems Chemistry. Faculty Host: Tim Cernak ( [email protected] ) Speaker Abstract
Zoom link	January 20, 2022 4:00pm Virtual Zoom link	Di Wang Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Development of Total Synthesis Strategies and Application to Phenylspirodrimanes Faculty Host: Tim Cernak ( [email protected] ) Speaker Abstract
Zoom link	January 27, 2022 4:00pm Virtual Zoom link	Marcy Balunas, PhD Associate Professor of Medicinal Chemistry Department of Pharmaceutical Sciences, University of Connecticut Regulation of specialized metabolite production in complex microbiome systems Faculty Host: David Sherman ( [email protected] ) Speaker Abstract
Zoom link	February 16, 2022 12:00pm Virtual Zoom link	Nir London, PhD Senior Scientist Weizmann Institute Covalent inhibitors - from discovery to function Faculty Host: Ashu Tripathi ( [email protected] ) Speaker Abstract
https://umich.zoom.us/j/99924326067	March 3, 2022 4:00pm 1544 NUB https://umich.zoom.us/j/99924326067	Jack Li, PhD Vice President of Chemistry ChemPartner A Chemistry Journey of Targeted Protein Degraders Faculty Host: Tim Cernak ( [email protected] ) Speaker Abstract
Zoom link	April 7, 2022 4:00pm Virtual Zoom link	Shanteri Singh, PhD Assistant Professor Department of Chemistry and Biochemistry, University of Oklahoma Late-stage diversification of natural products using aromatic prenyltransferases Faculty Host: Ashu Tripathi ( [email protected] ) Speaker Abstract
Password: medchem	April 14, 2022 4:00pm Palmer Commons, Forum Hall Password: medchem	Kevan Shokat, PhD Professor, Department of Cellular and Molecular Pharmacology, UCSF and Professor, Department of UC Berkeley University of California, San Francisco, and University of California, Berkeley, and Invesigator, Howard Hughes Medical Institute Shaomeng Wang Award Lecture Faculty Host: Shaomeng Wang ( [email protected] ) Speaker Website
Password: Rhohlman22	April 15, 2022 10:00am Palmer Commons Forum Hall Password: Rhohlman22	Robert Hohlman Medicinal Chemistry PhD Defense College of Pharmacy, University of Michigan Harnessing Cascade Biocatalysis for the Chemoenzymatic Synthesis of Unnatural Hapalindole-Type Metabolites and Further Exploration into their Biosynthesis Faculty Host: David Sherman ( [email protected] ) Speaker Abstract
	April 21, 2022 9:00am NCRC Research Auditorium	Atsunori Kaneshige Medicinal Chemistry PhD Defense College of Pharmacy, University of Michigan Development of a first-in-class STAT5 PROTAC degrader Faculty Host: Shaomeng Wang ( [email protected] ) Speaker Abstract
	May 19, 2022 4:00pm Palmer Commons, Forum Hall	John W. Tomsho, PhD Director, Graduate Programs in Chemistry, Biochemistry and Pharmacognosy; Co-Director, Chemistry Core Facility; NMR Facility Director; Associate Professor of Chemistry and Biochemistry University of the Sciences Boron-containing Analogs of Fosmidomycin: Synthesis and Antibacterial Properties Faculty Host: Heather Carlson ( [email protected] ) Speaker Abstract
https://www.lsi.umich.edu/events/2022-09/annual-u-m-drug-discovery-symposium	September 21, 2022 9:00am Rackham Building https://www.lsi.umich.edu/events/2022-09/annual-u-m-drug-discovery-symposium	Nicholas Meanwell, PhD Vice President, Bristol-Myers Squibb Annual U-M Drug Discovery Symposium
	October 13, 2022 4:00pm 2548 NUB	Adam Shuhendler, PhD Associate Professor and Canada Research Chair, Department of Chemistry & Biomolecular Sciences; Scientist, University of Ottawa Heart Institute University of Ottawa Watching it all go bad: Exploiting dynamic reactivity for molecular imaging Faculty Host: Peter Scott ( [email protected] ) Speaker Abstract
	October 27, 2022 4:00pm 2548 NUB	Mary Kay Pflum, PhD Professor of Chemistry Wayne State University Kinase-catalyzed Labeling: Chemical Approaches to Mapping Cell Signaling Pathways Faculty Host: Peter Toogood Speaker Abstract
	November 3, 2022 4:00pm 2548 NUB	Erik Hembre, PhD Associate Vice President Discovery Research and Technologies Eli Lilly and Co. Discovery of LY3154885, a Second Generation Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Drug-Drug Interaction Risk Profile Faculty Host: Peter Toogood Speaker Abstract
	November 4, 2022 4:00pm CCCB 0420	Shireen Ashkar Medicinal Chemistry PhD Defense College of Pharmacy, University of Michigan Development and Discovery of Novel Inhibitors of Mycobacterium tuberculosis RNA Polymerase for the Treatment of Tuberculosis Faculty Host: George Garcia ( [email protected] ) Speaker Abstract
	November 10, 2022 4:00pm 2548 NUB	Larry Hamann, PhD Co-Founder and CEO Interdict Bio The Arc of Innovation in Small Molecule Drug Discovery: Past, Present & Future
Password: 393874	November 10, 2022 2:00pm Rackham 4th Floor East Conference Room Password: 393874	Nicholas Ragazzone Medicinal Chemistry PhD Defense College of Pharmacy, University of Michigan Elucidating Protein-DNA Recognition by the Bacterial Transcription Factors MarA and VirF by Homology Modeling and DNA-binding Studies of Wild-type and Mutant MarA and VirF Faculty Host: George Garcia ( [email protected] ) Speaker Abstract
Password: 248732	November 16, 2022 1:15pm Virtual Password: 248732	Garrett Dow Medicinal Chemistry PhD Defense College of Pharmacy, University of Michigan Elucidation of DNA-Binding and Dimerization Activities of the Master Virulence Transcription Factor, VirF, From Shigella flexneri to Aid in Virulence-Targeted Inhibitor Design for Treatment of Shigellosis Faculty Host: George Garcia ( [email protected] ) Speaker Abstract
	November 17, 2022 4:00pm Palmer Commons Forum Hall	Gunda Georg, PhD Regents Professor of Medicinal Chemistry, Robert Vince Endowed Chair, McKnight Presidential Chair University of Minnesota Discovery and development of a novel contraceptive for men Faculty Host: Martin Clasby Speaker Abstract
Password: Dicer	November 28, 2022 10:00am LSI Library Password: Dicer	Rachel Torrez Medicinal Chemistry PhD Defense College of Pharmacy, University of Michigan Structural and Functional Analysis of Human Dicer Faculty Host: Amanda Garner ( [email protected] )
	December 16, 2022 9:00am 1544 NUB	Jesse Wotring Medicinal Chemistry PhD Defense College of Pharmacy, University of Michigan Rapidly Translational Drug Discovery Using High Content Imaging: Applications to Non-Alcoholic Fatty Liver Disease and the COVID-19 Pandemic Faculty Host: Jonny Sexton ( [email protected] ) Speaker Abstract
	January 19, 2023 4:00pm 2548 NUB	Jay Schneekloth, PhD Senior Investigator, Chemical Biology Laboratory; Head, Chemical Genetics Section National Cancer Institute Tools and Tactics for Targeting RNA with Small Molecules Faculty Host: Amanda Garner Speaker Abstract
Passcode: 250708	January 26, 2023 4:00pm 2548 NUB Passcode: 250708	Dalia Soueid Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Cell-Based Assay Development Strategies for the Detection and Validation of Aberrant mRNA-Protein Interactions Faculty Host: Amanda Garner ( [email protected] ) Speaker Abstract
	February 7, 2023 4:00pm 2548 NUB	Adam Ard Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Discovery and development of small molecule sarcoplasmic reticulum Ca2+-ATPase (SERCA) activators for the treatment of diastolic dysfunction Faculty Host: Martin Clasby ( [email protected] ) Speaker Abstract
	February 9, 2023 4:00pm 2548 NUB	Mason Baber Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Discovery and Optimization of Pyruvate Dehydrogenase Kinase (PDHK) Inhibitors for Modulation of Tumor Metabolism Faculty Host: Peter Toogood ( [email protected] ) Speaker Abstract
	February 14, 2023 4:00pm 2548 NUB	Mya Gough Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Design, Synthesis, and Evaluation of Novel PDHK Inhibitors as a Therapeutic Treatment for Cancer Faculty Host: Peter Toogood ( [email protected] ) Speaker Abstract
Passcode: 916566	February 16, 2023 4:00pm 2548 NUB Passcode: 916566	Jordan Hungerford Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Elucidation of a BNM2 BURP domain biosynthetic pathway in Ziziphus jujuba Faculty Host: Roland Kersten ( [email protected] ) Speaker Abstract
Passcode: 288153	February 21, 2023 4:00pm 2548 NUB Passcode: 288153	Sophia Meyer Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Precision-Medicine Models for Predicting Immune-Mediated Drug Efficacy and Toxicity Faculty Host: Jonny Sexton ( [email protected] ) Speaker Abstract
Passcode: medchem	February 27, 2023 10:00am 2548 NUB Passcode: medchem	Yuning Shen Medicinal Chemistry PhD Defense College of Pharmacy, University of Michigan High Throughput Experimentation Facilitated Development of Amine-Acid Cross Coupling Reactions Faculty Host: Tim Cernak ( [email protected] ) Speaker Abstract
	February 28, 2023 4:00pm 2548 NUB	Andrew Outlaw Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Development of a High-Throughput FRET-Based Assay to Enable Rapid Amine-Acid Reaction Discovery Faculty Host: Tim Cernak ( [email protected] ) Speaker Abstract
	March 9, 2023 4:00pm 2548 NUB	Dionicio Siegel, PhD Professor, Skaggs School of Pharmacy and Pharmaceutical Sciences University of California, San Diego Accessing, Understanding, and Optimizing Natural Products Through Chemical Synthesis Faculty Host: Tim Cernak ( [email protected] ) Speaker Abstract
	March 14, 2023 4:00pm 2548 NUB	Ruheng Zhao Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Development of Novel C–C Coupling Reactions from Amines and Acids Faculty Host: Tim Cernak ( [email protected] ) Speaker Abstract
	March 16, 2023 4:00pm 2548 NUB	Erika Taylor, PhD Associate Professor of Chemistry Wesleyan University Drug Discovery and E. coli HeptosyltransferaseI - How basic science research might change our understanding of antibiotic mechanism of action Faculty Host: Peter Toogood ( [email protected] ) Speaker Abstract
Passcode:689854	March 21, 2023 4:00pm 2548 NUB Passcode:689854	Khadija Shafiq Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Systematic discovery of plant natural products for the development of lung cancer therapeutics Faculty Host: Jonny Sexton ( [email protected] ) Speaker Abstract
	April 20, 2023 4:00pm Palmer Commons Forum Hall	Craig Crews, PhD John C. Malone Professor of Molecular, Cellular, and Developmental Biology and Professor of Chemistry, of Pharmacology, and of Management; Executive Director, Yale Center for Molecular Discovery Yale University PROTACs and Targeted Protein Degradation: A New Therapeutic Modality Faculty Host: Shaomeng Wang ( [email protected] ) Speaker Abstract
Passcode: medchem	September 7, 2023 11:00am 1544 NUB Passcode: medchem	Nichole Klatt, PhD Professor and the Director of the Division of Surgical Outcomes and Precision Medicine Research, Department of Surgery University of Minnesota Novel mechanisms underlying microbiome-mediated influence on human health Faculty Host: Emily Scott ( [email protected] ) Speaker Abstract
Passcode: medchem	September 28, 2023 11:00am 1544 NUB Passcode: medchem	Sloan Devlin, PhD Associate Professor in the Department of Biological Chemistry and Molecular Pharmacology Harvard Medical School Host-produced, bacterially modified gut metabolites Faculty Host: Marcy Balunas ( [email protected] ) Speaker Abstract
Passcode: medchem	October 5, 2023 11:00am 1544 NUB Passcode: medchem	Vincent Njar, PhD Professor University of Maryland School of Medicine The Resurrection of Galeterone and Development of The Next Generation Galeterone Analogs (NGGAs) for Prostate Cancer Therapy (Drug Discovery: Ingenuity and Serendipity or Is it the Other Way Around?) Faculty Host: Nouri Neamati ( [email protected] ) Speaker Abstract
Passcode: medchem	October 19, 2023 11:00am 1544 NUB Passcode: medchem	Jessica Reed, PhD Vice President of Development Genetobe and Diapin Therapeutics Life After Graduate School – Discovery to Development and Dacomitinib to DT-678 Faculty Host: Mya Gough and Kathryn Hoegman Speaker Abstract
Zoom Link (Passcode: medchem)	October 26, 2023 11:00am 1544 NUB Zoom Link (Passcode: medchem)	Jackie von Salm, PhD Co-founder and Chief Science Officer Psilera Bioscience Re-Imagining Tryptamine Psychedelics for Mental Health Disorders Faculty Host: Amanda Garner ( [email protected] ) Speaker Abstract
Passcode: medchem	November 2, 2023 11:00am 1544 NUB Passcode: medchem	Henry Vanbrocklin, PhD Professor of Radiology University of California, San Francisco Radiolabeled nanocarriers: Imaging tools for patient-based drug delivery Faculty Host: Peter Scott ( [email protected] ) Speaker Abstract
Passcode: medchem	November 9, 2023 11:00am 1544 NUB Passcode: medchem	Thomas Prisinzano, PhD Director of the Drug Discovery & Development Core University of Kentucky Development of Synthetic Opioid Rescue Agents Faculty Host: John Traynor ( [email protected] ) Speaker Abstract
Passcode: medchem	November 16, 2023 11:00am 1544 NUB Passcode: medchem	Alison Axtman, PhD Associate Professor, Strategic Genomics Consortium University of North Carolina Understanding the molecular basis of neurodegeneration Faculty Host: Peter Toogood ( [email protected] ) Speaker Abstract
Passcode: medchem	November 29, 2023 10:00am NCRC B10 Research Auditorium Passcode: medchem	Wenbin Tu Medicinal Chemistry PhD Defense College of Pharmacy, University of Michigan Development of Potent and Selective Small-Molecule PROTAC Degraders of SMARCA2 Protein Faculty Host: Shaomeng Wang ( [email protected] ) Speaker Abstract
Passcode: medchem	November 30, 2023 1:30pm 1544 NUB Passcode: medchem	Amy Newman, PhD Scientific Director of the NIDA IRP; Chief of the Molecular Targets and Medications Discovery Branch; Chief of the Medicinal Chemistry Section; Director of Medication Development Program NIH Dopamine D3 receptor-directed medication development for the treatment of substance use disorders: Rationale, progress, and challenges Faculty Host: Martin Clasby ( [email protected] ) Speaker Abstract
Zoom link	December 14, 2023 11:00am 1544 NUB Zoom link	Tim Cernak, PhD Assistant Professor of Medicinal Chemistry and Assistant Professor of Chemistry University of Michigan Chemical Synthesis Enabled by Information
	January 11, 2024 11:00am 1544 NUB	Madison Frazier Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Diagnosing Dementia: The Clinical Evaluation of [11C]COU and Synthesis of [18F]COU Analogue for Preclinical Studies of Neurodegeneration Faculty Host: Peter Scott ( [email protected] ) Speaker Abstract
Passcode: 035744	January 18, 2024 12:00pm Rackham West Conference Room Passcode: 035744	Andrew McGrath Medicinal Chemistry PhD Defense College of Pharmacy, University of Michigan The Development of Unorthodox Amine– Acid Coupling Reactions and Their Applications Towards Complex Molecules for a Systems Approach to Chemistry Faculty Host: Tim Cernak ( [email protected] ) Speaker Abstract
Password: GoBlue144	January 18, 2024 11:00am 1544 NUB Password: GoBlue144	Tim Emmel Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Application of Constrained Glycosyl Fluorides for the Development of Complex Oligosaccharide Natural Products Faculty Host: John Montgomery ( [email protected] ) Speaker Abstract
Zoom link	January 25, 2024 12:00pm 1544 NUB Zoom link	Sahar Amin Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Diversification of Mitragynine Using Biocatalytic Approaches for Improved Therapeutics Faculty Host: David Sherman ( [email protected] ) Speaker Abstract
Zoom link	February 1, 2024 11:00am 1544 NUB Zoom link	Kathryn Hoegeman Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Development and Optimization of Lead Scaffolds for the Treatment of Non-Alcoholic Fatty Liver Disease (NAFLD) Faculty Host: Martin Clasby ( [email protected] ) Speaker Abstract
Zoom link	February 8, 2024 11:00am 1544 NUB Zoom link	Yu-Ting Kao Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Miniaturized synthesis and direct-to-biology accelerate drug discovery from natural products Faculty Host: Tim Cernak ( [email protected] ) Speaker Abstract
Passcode: medchem	February 15, 2024 11:00am 1544 NUB Passcode: medchem	Rachel O'Rourke Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Biological characterization of small molecule eIF4E inhibitors to assess their therapeutic potential in cancer Faculty Host: Amanda Garner ( [email protected] ) Speaker Abstract
Passcode: medchem	February 22, 2024 11:00am 1544 NUB Passcode: medchem	Derrick Ousley Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Plant Transcriptome Mining of Macrocyclic Peptides for In Silico Drug Discovery Faculty Host: Roland Kersten ( [email protected] ) Speaker Abstract
	March 7, 2024 11:00am 1544 NUB	Austin Ventura Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Strategic Catalytic Reactions for the Synthesis of Biologically Active Chemical Motifs for Small Molecule Drugs Faculty Host: John Montgomery ( [email protected] ) Speaker Abstract
Passcode: Ga68	March 14, 2024 11:00am 1544 NUB Passcode: Ga68	Ivan Wang Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Cyclotron Production of Gallium-68 and the Monitoring of Nuclear Medicine Therapies Faculty Host: Peter Scott ( [email protected] ) Speaker Abstract
Passcode: medchem	April 11, 2024 11:00am Palmer Commons Great Lakes South Passcode: medchem	Jeffery Kelly, PhD Lita Annenberg Hazen Professor of Chemistry Department of Chemistry, Scripps Research Pharmacological Adaptation of Proteostasis to Ameliorate Aging-associated Degenerative Diseases Faculty Host: Shaomeng Wang ( [email protected] ) Speaker Abstract
Passcode: medchem	April 18, 2024 2:00pm Palmer Commons Forum Hall Passcode: medchem	Lee Cronin, PhD Regius Chair of Chemistry University of Glasgow Will Chemputers Dream of Electric Drugs? Faculty Host: Tim Cernak ( [email protected] ) Speaker Abstract
	July 18, 2024 1:00pm Rackham East Conference Room	Katie Guild Medicinal Chemistry PhD Defense College of Pharmacy, University of Michigan TBD Faculty Host: George Garcia ( [email protected] )
	July 24, 2024 1:00pm Rackham East Conference Room	Luis Cervantes Medicinal Chemistry PhD Defense College of Pharmacy, University of Michigan TBD Faculty Host: Charles Brooks ( [email protected] )
Passcode: medchem	September 12, 2024 11:00am 1544 NUB Passcode: medchem	Jorge Ruas, PhD Professor of Pharmacology University of Michigan Developing exercise-based pharmacological treatments: from metabolism to mental health Faculty Host: Amanda Garner ( [email protected] ) Speaker Abstract
Passcode: medchem	September 19, 2024 11:00am 1544 NUB Passcode: medchem	Dennis Liotta, PhD Professor, Department of Chemistry Emory College of Arts and Sciences Making New Drugs the Hard Way Faculty Host: Katelyn Brown ( [email protected] ) Student Host: Kathryn Hoegeman ( [email protected] ) Speaker Abstract
Passcode: medchem	October 3, 2024 11:00am 1544 NUB Passcode: medchem	Sandra Loesgen, PhD Professor, Department of Medicinal Chemistry University of Florida Discovery of bioactive natural products from unique ecosystems and behavior guided assays Faculty Host: Roland Kersten ( [email protected] ) Speaker Abstract
Passcode: medchem	October 17, 2024 11:00am 1544 NUB Passcode: medchem	Dean Brown, PhD Senior VP, Head of Discovery Science Jnana Therapeutics Discovery and characterization of JNT-517, an inhibitor of SLC6A19 for the treatment of phenylketonuria Faculty Host: Amanda Garner ( [email protected] ) Speaker Abstract
Passcode: medchem	October 24, 2024 11:00am 1544 NUB Passcode: medchem	Mohamed Donia, PhD Associate Professor, Department of Chemical Engineering Princeton University Production and metabolism of bioactive small molecules by the human microbiome Faculty Host: Roland Kersten ( [email protected] ) Speaker Abstract
Passcode: medchem	October 31, 2024 11:00am 1544 NUB Passcode: medchem	Mike Ameriks, PhD Sr. Scientific Director, Discovery Chemistry Johnson & Johnson Inhibition of Endocannabinoid Metabolism as a Strategy to Treat Psychiatric Disorders Faculty Host: Jason Rech ( [email protected] ) Speaker Abstract
Passcode: medchem	November 7, 2024 11:00am 1544 NUB Passcode: medchem	J. P. Gerdt, PhD Assistant Professor, Department of Chemistry Indiana University Chemical Inhibition of Bacterial Immune Systems Faculty Host: Marcy Balunas ( [email protected] ) Speaker Abstract
	November 13, 2024 2:00PM Michigan League - Hussey Room (2nd Floor)	Mark Murcko, PhD Interim Chief Scientific Officer, Dewpoint Therapeutics; Senior Lecturer, Department of Biological Engineering MIT Transferrable Lessons in Drug Discovery Faculty Host: VMCC (Jason Rech and Martin Clasby) ( [email protected] ) Speaker Abstract
Passcode: medchem	December 5, 2024 11:00am 1544 NUB Passcode: medchem	Jon Ellman, PhD Eugene Higgins Professor of Chemistry and Professor of Pharmacology, Department of Chemistry Yale University New Catalytic Methods for the Preparation of Pharmaceutically Relevant Structures Faculty Host: Jason Rech ( [email protected] ) Speaker Abstract
	January 21, 2025 4:30pm 2548 NUB	Tim Borel Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Design and Optimization of Toxoplasma gondii Cathepsin Protease L (TgCPL) Inhibitors for the Treatment of Toxoplasmosis Faculty Host: Martin Clasby ( [email protected] ) Speaker Abstract
	January 21, 2025 4:00pm 2548 NUB	Hannah Boesger Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Targeted Genome Mining of Anticancer Natural Products Faculty Host: David Sherman ( [email protected] ) Speaker Abstract
	January 30, 2025 11:00am 1544 NUB	Anupam Ojha, PhD Research Fellow Flatiron Institute Next-generation multiscale computational frameworks integrating quantum mechanics, molecular simulations, Brownian dynamics, and cryo-EM for AI-driven drug discovery Faculty Host: Emily Scott ([email protected]) and Terra Sztain ([email protected])
	February 4, 2025 4:00pm 2548 NUB	Brandon Klein Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Development of Chemotranscriptomics: Affinity-Based RNA Profiling for the Detection of Ligandable Interfaces of RNAs and RNA-Binding Proteins Faculty Host: Amanda Garner [email protected] Speaker Abstract
	February 4, 2025 4:30pm 2548 NUB	Youngseo Na Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Development of Inhalable Lipid Nanoparticles for the Treatment of Lung Cystic Fibrosis: Overcoming Barriers to CFTR Gene Deliver Faculty Host: Anna Schwendeman ( [email protected] ) Speaker Abstract
	February 6, 2025 11:00am 1544 NUB	Akos Nyerges, PhD Research Associate Harvard Medical School, Department of Genetics Synthetic Genomes and Genetic Codes for Virus Resistance, Biocontainment, and Therapy Faculty Host: Emily Scott ([email protected]) and Terra Sztain ([email protected])
	February 11, 2025 4:00pm 2548 NUB	Jennifer Nguyen Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Investigating the therapeutic potential of gut microbe-derived metabolites in colorectal cancer Faculty Host: Marcy Balunas [email protected] Speaker Abstract
	February 11, 2025 4:30pm 2548 NUB	Chih-Jung Chen Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan Design and Development of Novel Malic Enzyme 1 Inhibitors for the Treatment of Pancreatic Ductal Adenocarcinoma Faculty Host: Peter Toogood [email protected] Speaker Abstract
	February 13, 2025 11:00am 1544 NUB	Zhe Zhuang, PhD Research Assistant Stanford University Molecular Glue Discovery Enabled by Targeted Degron Display Faculty Host: Emily Scott ([email protected]) and Terra Sztain ([email protected])
	February 18, 2025 4:00pm 2548 NUB	Katelyn Brown Medicinal Chemistry PhD Candidate, Third-Year Student Seminar College of Pharmacy, University of Michigan TBD
	February 20, 2025 11:00am 1544 NUB	Yuyan Jiang, PhD Research Associate Stanford University TBD Faculty Host: Emily Scott ([email protected]) and Terra Sztain ([email protected])
	March 6, 2025 11:00am 1544 NUB	Conor Coley, PhD Associate Professor Massachusetts Institute of Technology TBD Faculty Host: Peter Scott ( [email protected] )
	April 17, 2025 11:00am 1544 NUB	Ron Jenkins, PhD Executive Director, Tech Ops University of Michigan TBD Faculty Host: George Garcia ( [email protected] )
	April 24, 2025 11:00am 1544 NUB	Maria-Jesus Blanco, PhD Senior Vice President, Head of Drug Discovery Atavistik Bio TBD Faculty Host: Amanda Garner ( [email protected] )

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