Core Faculty

  Name / Title / Lab Contact Info Research Interests

Mustapha Beleh, PhD
Director of Education and Lecturer in Medicinal Chemistry

Phone:  734/647-9459
Email:  mbeleh@umich.edu

Room:  2565 NUB

 

Heather Carlson, PhD
Professor of Medicinal Chemistry, College of Pharmacy, and Professor of Chemistry, College of Literature, Science, and the Arts

Lab

ACCEPTING STUDENTS

Phone:  734/615-6841
Email:  carlsonh@umich.edu

Room: 2555 NUB

The Carlson lab studies protein-ligand interactions through theoretical chemistry and computer simulations.  Projects range from studying the basic biophysics of molecular recognition to applying drug discovery techniques to mining databases for cheminformatics insights.  Research interests include protein structure and dynamics, allosteric control, binding hotspots, lead discovery, polypharmacology, and large chemical databases.

Timothy Cernak
Assistant Professor of Medicinal Chemistry, College of Pharmacy, and Assistant Professor of Chemistry, College of Literature, Science, and the Arts


Lab

ACCEPTING STUDENTS

Phone:  734/647-6793
Email:  tcernak@umich.edu

Room: 3815 Chem

 

The Cernak Lab is developing an interface between chemical synthesis and data science. They explore reaction discovery and total synthesis using a Big Data approach. Synthetic reactions are run in the lab both in traditional format, and using modern robotic and high-throughput methods. The molecules generated are used in cell imaging, microscopy, and chemical biology studies. Applied areas of interest include therapeutics for cancer, infection, and neurological disease as well as perfumes.

Martin Clasby
Research Assistant Professor of Medicinal Chemistry and Co-director of the Vahlteich Medicinal Chemistry Core

VMCC

ACCEPTING STUDENTS

Phone:  734/647-1949
Email:  mclasby@umich.edu

Room:  3632 Chem

In the VMCC we design and synthesize drug-like molecules and diagnostic probes for use in biomedical research.  Our graduate students and staff collaborate with other biomedical researchers in translating novel therapeutic hypotheses into proof-of-concept in animal models of disease regardless of therapeutic area.  We have established many productive collaborations with labs within the University and at external institutions.

George Garcia, PhD
Professor and Chair of Medicinal Chemistry and Director, Interdepartmental Program in Medicinal Chemistry

Lab
 

Phone:  734/764-2202
Email:  gagarcia@umich.edu

Room:  4567 NUB

 
Amanda Garner, PhD
Assistant Professor of Medicinal Chemistry

Lab

ACCEPTING STUDENTS
 

Phone:  734/763-2654
Email:  algarner@umich.edu

Room:  B520 Rm 3343 NCRC

The Garner Laboratory uses chemical biology, medicinal chemistry and molecular and cellular biology approaches to investigate the high-risk/high-reward areas of targeting microRNAs, RNA-protein and protein-protein interactions for probe and drug discovery. These efforts are part of our larger interest in studying mechanisms of translational control, which are dysregulated in many human diseases, yet remain underexplored for therapeutic development.

Roland Kersten
Assistant Professor

Lab

ACCEPTING STUDENTS

Phone:  734/647-1840
Email:  rkersten@umich.edu

Room:  4062 NUB

The Kersten lab aims to discover new plant-based chemicals to cure human diseases by combination of ancient wisdom about medicinal plants and modern knowledge of plant biochemistry. We use plant genomics, mass spectrometry and synthetic biology to unlock new medicinal chemistry from plants.

Scott Larsen, PhD
Joseph Burckhalter Collegiate Research Professor of Medicinal Chemistry and Co-director of the Vahlteich Medicinal Chemistry Core

VMCC

Phone:  734/615-0454
Email:  sdlarsen@umich.edu

Room:  3638 Chem

In the VMCC we design and synthesize drug-like molecules and diagnostic probes for use in biomedical research.  Our graduate students and staff collaborate with other biomedical researchers in translating novel therapeutic hypotheses into proof-of-concept in animal models of disease regardless of therapeutic area.  We have established many productive collaborations with labs within the University and at external institutions.

Henry Mosberg, PhD
Tom D. Rowe Collegiate Professor of Medicinal Chemistry

Lab
 

Phone:  734/764-8117
Email:  him@umich.edu

Room:  3555 NUB

Research in the Mosberg lab focuses primarily on molecular recognition between small to medium size ligands (usually peptides) and their macromolecular targets (usually membrane-associated, G protein-coupled receptors, GPCRs) and spans structure-based drug design and synthesis, combinatorial synthesis, protein structure modeling, and biochemical characterization.

Nouri Neamati, PhD
John G. Searle Professor of Medicinal Chemistry

ACCEPTING STUDENTS

Phone:  734/647-2732
Email:  neamati@umich.edu

Room:  B520-1363 NCRC

 
Emily Scott
Professor of Medicinal Chemistry, College of Pharmacy; Professor of Pharmacology, Medical School; and Professor of Biophysics, College of Literature, Science, and the Arts

Lab

ACCEPTING STUDENTS

Phone:  734/764-3530
Email:  scottee@umich.edu

Room:  2020 Pharm

The Scott lab studies structure/function of human cytochrome P450 enzymes involved in 1) drug metabolism and procarcinogen activation and 2) generation of important endogenous steroids, fatty acids, and eicosanoids. Understanding the former P450 enzymes is important in predicting drug dosing and adverse effects, while the latter are drug targets in many diseases.  Biochemical, biophysical, and structural biology approaches are employed.

Johnathan Sexton
Assistant Professor of Internal Medicine, Medical School, and Assistant Professor of Medicinal Chemistry, College of Pharmacy

Lab

ACCEPTING STUDENTS

 

Phone:  734/764-1550
Email:  jzsexton@umich.edu

Room:  4742F Med Sci II

The Sexton lab performs drug discovery and development for the interrelated set of disorders involving diabetes, obesity, metabolic syndrome and associated complications. We use a combination of phenotypic and molecular target driven approaches with core competencies in diabetes, fatty liver disease, and metabolic coupled with in vivo models of diabetes and obesity. Our main technology focus is high content screening and cell painting.

David Sherman, PhD
Hans W. Vahlteich Professor of Medicinal Chemistry, College of Pharmacy; Professor of Microbiology and Immunology, Medical School; Professor of Chemistry, College of Literature, Science, and the Arts; and Research Professor, Life Sciences Institute

Lab

ACCEPTING STUDENTS

Phone:  734/615-9907
Email:  davidhs@umich.edu

Room:  4036 LSI

Sherman pursues research on natural product drug discovery.  His laboratory has developed a unique library of compounds and extracts that are being screened against numerous disease targets relating to cancer, microbial pathogens, cardiovascular disease, diabetes, and human parasites.  Sherman’s research includes genomic analysis of diverse microorganisms that generate natural products in an effort to understand their assembly, structural diversification and modes of self-resistance.

John Traynor


Edward F Domino Research Professor
Professor of Medicinal Chemistry, College of Pharmacy
Professor and Associate Chair for Research, Department of Pharmacology, Medical School

Lab
Domino Research Center

ACCEPTING STUDENTS

Phone:  734/647-7479
Email:  jtraynor@umich.edu

Room:  1220C MSRB 3

Research in the Traynor laboratory is centered on drugs that act at opioid receptors to give analgesia, but have on-target side-effects including life-threatening respiratory depression and addiction.  We use biochemical, pharmacological and computational methods to understand how opioid receptors work and to design novel ligands that target these receptors, and associated proteins, to develop medications for pain and substance abuse.

Ashootosh Tripathi
Assistant Research Scientist, Life Sciences Institute, and Research Assistant Professor of Medicinal Chemistry, College of Pharmacy

Lab

ACCEPTING STUDENTS

Phone:  734/647-8988
Email:  ashtri@umich.edu

Room:  4314A LSI

Tripathi's core laboratory works towards unraveling the microbial chemical diversity identified through HTS and connecting the producing biosynthetic gene clusters to the novel/unknown chemical entities by utilizing state-of-the-art technologies in Natural Products Discovery Core. Furthermore, the rapid genomic and metabolomics profiling allows users to identify high-value molecules, as well as, novel enzymes as probes, drug leads, and tools.

Shaomeng Wang, PhD
Warner-Lambert/Parke-Davis Professor of Internal Medicine, Medical School, and Professor of Medicinal Chemistry, College of Pharmacy

Lab

ACCEPTING STUDENTS

Phone:  734/615-3969
Email:  shaomeng@umich.edu

Room:  1245/NCRC 520

 
Andrew White, PhD
Research Associate Professor of Medicinal Chemistry and Director of the Vahlteich Medicinal Chemistry Core

VMCC

ACCEPTING STUDENTS

Phone:  734/647-7374
Email:  whitandd@umich.edu

Room:  4563 NUB

In the VMCC we design and synthesize drug-like molecules and diagnostic probes for use in biomedical research.  Our graduate students and staff collaborate with other biomedical researchers in translating novel therapeutic hypotheses into proof-of-concept in animal models of disease regardless of therapeutic area.  We have established many productive collaborations with labs within the University and at external institutions.

 

Affiliated Faculty in the Interdepartmental Program in Medicinal Chemistry

  Name / Title / Lab Contact Info Research Interests
Charles Brooks III, PhD
Warner-Lambert/Parke-Davis Professor of Chemistry and Professor of Biophysics, College of Literature, Science, and the Arts, and Faculty Associate in the Interdepartmental Program in Medicinal Chemistry

Lab

ACCEPTING STUDENTS
 

Phone:  734/647-6682
Email:  brookscl@umich.edu
 

Room:  2006 Chem

 
Y. Eugene Chen
Frederick Huetwell Professor of Cardiovascular Medicine Professor of Cardiac Surgery, Physiology, and Pharmacology Vice-Chair for Basic and Translational Research, Department of Cardiac Surgery Director, Center for Advanced Models for Translational Sciences and Therapeutics University of Michigan Medical Center

Lab

ACCEPTING STUDENTS

Phone:  734/647-5742
Email:  echenum@umich.edu

Room:  B26 Rm 361S NCRC

 
Jolanta Grembecka, PhD
Assistant Professor of Pathology, Medical School, and Faculty Associate in the Interdepartmental Program in Medicinal Chemistry

Lab

ACCEPTING STUDENTS

Phone:  734/615-3860
Email:  jolantag@umich.edu

Room:  4510D MSRB 1 Pathology

 
John Montgomery, PhD
Margaret and Herman Sokol Professor of Medicinal Chemistry and Professor of Chemistry, College of Literature, Science, and the Arts, and Faculty Associate in the Interdepartmental Program in Medicinal Chemistry

Lab

ACCEPTING STUDENTS

Phone:  734/764 4424
Email:  jmontg@umich.edu

Room:  3819 Chem

 
Pavel Nagorny, PhD
Assistant Professor of Chemistry, College of Literature, Science, and the Arts, and Faculty Associate in the Interdepartmental Program in Medicinal Chemistry


Lab

ACCEPTING STUDENTS

Phone:  734/615-2833
Email:  nagorny@umich.edu

Room:  3807 Chem

 

Alison Narayan, PhD
William R. Roush Assistant Professor, Department of Chemistry, Research Assistant Professor, Life Sciences Institute and Assistant Professor of Chemistry, College of Literature, Science, and the Arts

ACCEPTING STUDENTS

Phone:  734/615-6873
Email:  arhardin@umich.edu

Room:  4002 LSI

 
Zaneta Nikolovska-Coleska, PhD
Associate Professor of Pathology, Medical School, and Director Molecular and Cellular Pathology Graduate Program

Lab

ACCEPTING STUDENTS

Phone:  734/615-9202
Email:  zanetan@umich.edu

Room:  B520 Rm 1368

 
Melanie Ohi
Research Associate Professor, Life Sciences Institute: Associate Professor of Cell and Developmental Biology, Medical School; and Faculty Associate in the Interdepartmental Program in Medicinal Chemistry

ACCEPTING STUDENTS

Phone:  734/763-6493
Email:  mohi@umich.edu

Room:  6th Floor LSI

 
Bruce Palfey, PhD
Associate Professor of Biological Chemistry, Medical School; Associate Director, Chemical Biology Program, Rackham Graduate School; and Faculty Associate in the Interdepartmental Program in Medicinal Chemistry

Lab

ACCEPTING STUDENTS

Phone:  734/615-2452
Email:  brupalf@umich.edu

Room:  5220E MSRB 3 BioChem

 
Anna Schwendeman, PhD
Associate Professor of Pharmaceutical Sciences

ACCEPTING STUDENTS

Phone:  734/763-4056
Email:  annaschw@umich.edu

Room:  B20 Rm 102W NCRC

 
Peter Scott, PhD
Research Investigator in Radiology, Medical School, and Faculty Associate in the Interdepartmental Program in Medicinal Chemistry

Lab

ACCEPTING STUDENTS

Phone:  734/615-1756
Email:  pjhscott@umich.edu

Room:  2298 Med Sci 1 Radiology

 
Janet Smith, PhD
Margaret J. Hunter Collegiate Professor in the Life Sciences and Professor of Biological Chemistry, Medical School; Research Professor, Life Sciences Institute; and Faculty Associate in the Interdepartmental Program in Medicinal Chemistry

Lab

ACCEPTING STUDENTS

Phone:  734/615-9564
Email:  janetsmi@umich.edu

Room:  3437 LSI

 
Duxin Sun, PhD
J. G. Searle Professor of Pharmaceutical Sciences, College of Pharmacy

Lab

ACCEPTING STUDENTS

Phone:  734/615-8740
Email:  duxins@umich.edu

Room:  B520 Rm 3353

 

 

Listing Row

Thursday, September 5, 2019
Thursday, September 5, 2019