The objective of the Clinical Pharmacy Translational Science (CPTS) PhD Program is to provide intensive didactic and mentored research training to post-graduates (PharmD, BS, etc.) with an interest in pursuing careers as independent investigators in research. Each student will select from two tracks for focused learning and training; Health Services Research (HSR) focuses on how health policy and our health systems and providers can impact and improve medication use, while Omics Research focuses on the discovery and translation of physiological biomarkers that can be used to predict, monitor, or understand treatment outcomes.

Curriculum

All students will receive general instruction in translational pharmaceutical sciences, research study design, and grant proposal development, and participate in a Seminar series with departmental faculty. In-depth knowledge and skills in HSR or Omics will be developed. We anticipate that students in the CTPS PhD Program will complete their doctoral studies in about four years. A general outline of the anticipated timeline and curricula for students within each track are provided in the below sections. Faculty of interest should be mentioned in application materials; however, we do not accept students into the program to do PhD work with specific faculty. There is no MS available. 

  • Year 1 Fall

    Students will meet with all professors in month one, and work in the lab of two to three professors who will be potential advisors.

    All students will take the following courses

    CP 7xx Introduction to clinical pharmaceutical translational sciences (2.0 credits). The purpose of this course is for the learner to understand the clinical and translational spectrum and to identify relevant and innovative research questions along the continuum, providing a foundation for future research. Key research articles and findings will be used to illustrate the mechanistic and theoretical bases for pharmaceutical clinical and translational research.

    CP 7xx Clinical trial and observational research designs (2.0). The purpose of this course is for the learner to gain knowledge in conducting clinical and observational trials, with a focus on threats to internal and external validity of these approaches. Innovative adaptive designs will also be included.

    BIOSTAT 521 Applied Biostatistics (4.0). Fundamental statistical concepts related to the practice of public health: descriptive statistics; probability; sampling; statistical distributions; estimation; hypothesis testing; chi-square tests; simple and multiple linear regression; one-way ANOVA. Taught at a more advanced mathematical level than Biostat 503. Use of the computer in statistical analysis.

    MC 660: Responsible conduct of research and scholarship in pharmaceutical sciences (0.5). This course teaches students about ethics and integrity in science.  It takes advantage of case studies that link basic principles with specific examples, providing students with opportunities to discuss and develop concepts related to ethics and scientific integrity.  A major teaching tool will be the use of case studies where students discuss model cases and are challenged to apply their own knowledge as well as their personal experiences and insights in order to derive appropriate solutions to the problems posed.  

    CP 7xx Clinical Pharmacy Seminar (1.0). Weekly or bi-weekly presentations of graduate students, faculty and/or visitors regarding current studies in pharmaceutical clinical and translational sciences. Professional development and skill development such as writing specific aims or giving job/chalk talks will also be included. Rotated among faculty

  • Year 1 Winter

    Students will indicate their primary mentor and work on a project in their mentor’s lab while working towards identifying their future research project.

    All students will take the following shared courses:

    BIOSTAT 522: Biostatistical Analysis for Health-related studies (3.0). A second course in applied biostatistical methods and data analysis. Concepts of data analysis and experimental design for health-related studies. Emphasis on categorical data analysis, multiple regression, analysis of variance and covariance.

    CP 7xx Preparing a research grant proposal (1.0). The purpose of this course is for the learner to gain knowledge and experience in writing innovative research questions and grant applications. The course consists of several interactive lectures and workshops about the process of grant writing. Students select a research topic for an NIH R03/R21-type grant proposal, complete a draft, and present it to the class for peer feedback.

    CP 7xx Clinical Pharmacy Seminar (1.0). See description above

    MC 660: Responsible conduct of research and scholarship in pharmaceutical sciences (0.5). See description above

    Students in the Omics track will also take the following courses:

    CP 8xx: Research methods in pharmaceutical –omics (3.0)
    CP 8xx: Oncology and pharmaceutical–omics (2.0)

    Students in the HSR track will also take the following courses:

    CP 8xx: Research methods in pharmacy health services research (3.0)
    CP 8xx: Clinical and patient-reported outcomes (2.0)

  • Year 1 Summer

    Students will continue to work with their primary advisor in the lab full-time, working to identify their dissertation research.

  • Year 2 Fall

    Students will write a proposal and present it in December of their second year, outlining the focus of their dissertation research in the graduate program. The proposal writing and defense will be the candidacy examination for the student. The proposal will be in the format of an R03 and may be supplemented by comprehensive literature review of 10-15 pages, as required by the primary mentor. The proposal will be defended in an oral examination, and the department faculty will serve as examiners of the candidacy examination.

    All students will take the following shared courses:

    CP 7xx Defending an original research proposal (1.0). Students finalize the research proposal drafted in CP 7xx and make an oral presentation to the class and faculty.

    CP 7xx Clinical Pharmacy Seminar (1.0). See description above

    Students in the Omics track will also take the following courses:

    CP 8xx: Pharmacogenomics and medication use (2.0)
    BIOSTAT 646: Molecular Genetics & Epigenetic Data (3.0)

    Students in the HSR track will also take the following courses:

    CP 8xx: Patient adherence to medications OR CP 8xx: eHealth solutions in pharmacy HSR (2.0)
    SOC 523: Qualitative Research Methods OR CP 870: Research methods in behavioral sciences (structural equation modeling) (3.0)

  • Year 2 Winter to Completion

    Students will continue working in the laboratory of their primary mentor until they have completed their dissertation research. Students are expected to complete all of their graduate training in the Winter or Summer of Year 4.  

    All students will take the following shared course:

    CP 7xx Clinical Pharmacy Seminar (1.0). See description above

    Students may also take up to one course per semester to supplement their training. 

Faculty Advisors

Our faculty conduct collaborative clinical-translational research that generally focuses within omics sciences and health services research. CPTS PhD Students will be matched with a primary advisor from the below list of tenure-track faculty members.

Omics Science

Amy Barton Pai
Peggy Carver
Vicki Ellingrod
Daniel Hertz
Jasmine Luzum
Bruce Mueller
Amit Pai
Kathleen Stringer 
Haojie Zhu

Health Services Research

Antoinette Coe
Michael P Dorsch
Steven Erickson
Karen B. Farris

Admissions

Successful applicants must demonstrate adequate preparation in pharmacy, chemistry, biochemistry and biology for the –omics track and pharmacy, informatics, economics or sociology for the HSR track. A prior PharmD degree is preferred, but not required. Some applicants may be required to take additional courses to enhance their background in any of these areas.

  • Procedures for applying to the CPTS PhD Program can be found HERE.
  • All materials must be submitted to Rackham Graduate School.
  • Applications are only accepted for Fall admission
  • Applications are made available in mid-September of the preceding year,
  • Application deadline is December 31, and decision notification letters are sent between January 15 and April 30.

Questions? Please e-mail CPTSPhD@umich.edu

Listing Row

Monday, October 16, 2017
Monday, October 16, 2017