Courses
Please visit the Curriculum page for a listing of required courses based on your research track.
Medicinal Chemistry 503
Real-World Drug Discovery (Cross-listed with Pharmacology 503) (Credits: 2)
U-M Department of Pharmacology, Life Sciences Institute, and Michigan Drug Discovery have developed a new course/program to provide relevant experience to trainees who are potentially interested in pursuing careers in pharma. Students will participate in “New Target Strategy Teams,” with each team researching and presenting their evaluation of a potential novel drug discovery project of interest to Michigan Drug Discovery. These teams will be organized and run very similarly to how these same kinds of teams operate in “big pharma;” and trainees will be making an important contribution to real-world decisions regarding which potential projects Michigan Drug Discovery and its collaborators will invest resources into.
Prerequisites: Permission of instructor
Instructor: Staff
Terms: Fall
Real-World Drug Discovery (Cross-listed with Pharmacology 503) (Credits: 2)
U-M Department of Pharmacology, Life Sciences Institute, and Michigan Drug Discovery have developed a new course/program to provide relevant experience to trainees who are potentially interested in pursuing careers in pharma. Students will participate in “New Target Strategy Teams,” with each team researching and presenting their evaluation of a potential novel drug discovery project of interest to Michigan Drug Discovery. These teams will be organized and run very similarly to how these same kinds of teams operate in “big pharma;” and trainees will be making an important contribution to real-world decisions regarding which potential projects Michigan Drug Discovery and its collaborators will invest resources into.
Prerequisites: Permission of instructor
Instructor: Staff
Terms: Fall
Medicinal Chemistry 532
Chemical Biology in Drug Discovery (Credits: 3)
This course covers topics in chemical biology as they are applied to the process of drug discovery, including the identification and validation of new targets and the development of novel therapeutic agents. The course will utilize a combination of lecture and primary literature discussion, as well as opportunities for students to gain skills in science communication and the preparation of research proposals.
Instructor: Staff
Terms: Fall
Chemical Biology in Drug Discovery (Credits: 3)
This course covers topics in chemical biology as they are applied to the process of drug discovery, including the identification and validation of new targets and the development of novel therapeutic agents. The course will utilize a combination of lecture and primary literature discussion, as well as opportunities for students to gain skills in science communication and the preparation of research proposals.
Instructor: Staff
Terms: Fall
Medicinal Chemistry 533
Survey of Therapeutics (Credits: 2)
Offered alternate Winter Terms. Survey of major drug classes with emphasis on molecular mechanisms of action. Target identification with chemical probes.
Prerequisites: Medicinal Chemistry 532 or permission of instructor
Instructor: Staff
Terms: Winter
Survey of Therapeutics (Credits: 2)
Offered alternate Winter Terms. Survey of major drug classes with emphasis on molecular mechanisms of action. Target identification with chemical probes.
Prerequisites: Medicinal Chemistry 532 or permission of instructor
Instructor: Staff
Terms: Winter
Medicinal Chemistry 534
Computational Principles of Medicinal Chemistry (Credits: 3)
Offered alternate Winter Terms. Survey of methods used in contemporary pharmaceutical research including computational and combinatorial approaches, and high-throughput analysis of drug efficacy and metabolism.
Prerequisites: Advisory: MedChem 532; Enforced: Graduate Standing or Permission of the Instructor
Instructor: Carlson
Terms: Winter
Computational Principles of Medicinal Chemistry (Credits: 3)
Offered alternate Winter Terms. Survey of methods used in contemporary pharmaceutical research including computational and combinatorial approaches, and high-throughput analysis of drug efficacy and metabolism.
Prerequisites: Advisory: MedChem 532; Enforced: Graduate Standing or Permission of the Instructor
Instructor: Carlson
Terms: Winter
Medicinal Chemistry 535
Principles of Drug Design (Credits: 3)
Sources of leads. Lead selection from HTS and virtual screening. General design principles. Drug design with defined target structure. Drug design without defined target structure. ADMET Optimization. Case Histories.
Prerequisites: MedChem 532 or Permission of Instructor
Instructor: Staff
Terms: Winter
Principles of Drug Design (Credits: 3)
Sources of leads. Lead selection from HTS and virtual screening. General design principles. Drug design with defined target structure. Drug design without defined target structure. ADMET Optimization. Case Histories.
Prerequisites: MedChem 532 or Permission of Instructor
Instructor: Staff
Terms: Winter
Medicinal Chemistry 573
Investigations in Medicinal Chemistry (Credits: 1-6)
Original investigation of a laboratory or library problem to be selected after consultation with the instructor. A paper is required.
Prerequisites: Permission of instructor
Instructor: Staff
Terms: Fall/Winter
Investigations in Medicinal Chemistry (Credits: 1-6)
Original investigation of a laboratory or library problem to be selected after consultation with the instructor. A paper is required.
Prerequisites: Permission of instructor
Instructor: Staff
Terms: Fall/Winter
Medicinal Chemistry 595
Machine Learning for Drug Discovery [Cross-listed with Bioinformatics 595] (Credits: 3)
This course introduces fundamental concepts and methods of chemoinformatics, structural biology, and machine learning. Discussion includes breakthroughs in scientific foundation model application, plus generalizability of drug discovery predictions. Emphasis is on understanding fundamental concepts in bioinformatics and practical application of data science tools and methods to problems in medicinal chemistry.
Prerequisites: Instructor Consent Required
Instructor: Staff
Terms: Winter
Machine Learning for Drug Discovery [Cross-listed with Bioinformatics 595] (Credits: 3)
This course introduces fundamental concepts and methods of chemoinformatics, structural biology, and machine learning. Discussion includes breakthroughs in scientific foundation model application, plus generalizability of drug discovery predictions. Emphasis is on understanding fundamental concepts in bioinformatics and practical application of data science tools and methods to problems in medicinal chemistry.
Prerequisites: Instructor Consent Required
Instructor: Staff
Terms: Winter
Medicinal Chemistry 635
Advanced Topics (Credits: 2)
Advanced Topics in Medicinal Chemistry
Prerequisites: Medicinal Chemistry 532 and 533 or permission of instructor
Instructor: Staff
Terms: Fall/Winter
Advanced Topics (Credits: 2)
Advanced Topics in Medicinal Chemistry
Prerequisites: Medicinal Chemistry 532 and 533 or permission of instructor
Instructor: Staff
Terms: Fall/Winter
Medicinal Chemistry 660
Responsible Conduct of Research and Scholarship in Pharmaceutical Sciences at the University of Michigan (Credits: 1 (half credit each term))
This course teaches students about ethics and integrity in science. It takes advantage of case studies that link basic principles with specific examples, providing students with opportunities to discuss and develop concepts related to ethics and scientific integrity. A major teaching tool will be the use of case studies where students discuss model cases and are challenged to apply their own knowledge as well as their personal experiences and insights in order to derive appropriate solutions to the problems posed. This course is aimed at the predoctoral students at the College of Pharmacy.
Prerequisites: Graduate students at the College of Pharmacy, with permission of instructor
Instructor: Staff
Terms: Fall/Winter
Responsible Conduct of Research and Scholarship in Pharmaceutical Sciences at the University of Michigan (Credits: 1 (half credit each term))
This course teaches students about ethics and integrity in science. It takes advantage of case studies that link basic principles with specific examples, providing students with opportunities to discuss and develop concepts related to ethics and scientific integrity. A major teaching tool will be the use of case studies where students discuss model cases and are challenged to apply their own knowledge as well as their personal experiences and insights in order to derive appropriate solutions to the problems posed. This course is aimed at the predoctoral students at the College of Pharmacy.
Prerequisites: Graduate students at the College of Pharmacy, with permission of instructor
Instructor: Staff
Terms: Fall/Winter
Medicinal Chemistry 740
Preparing a Research Grant Proposal (Credits: 1)
The course consists of several interactive lectures and workshops about the process of grant writing. The students select a research topic for an NIH R21-type grant propsal, complete a draft, and present it to the class for peer feedback.
Instructor: Staff
Terms: Fall
Preparing a Research Grant Proposal (Credits: 1)
The course consists of several interactive lectures and workshops about the process of grant writing. The students select a research topic for an NIH R21-type grant propsal, complete a draft, and present it to the class for peer feedback.
Instructor: Staff
Terms: Fall
Medicinal Chemistry 741
Defending an Original Research Proposal (Credits: 1)
The students finalize the research proposal drafted in MedChem 740 and make an oral presentation to their committee.
Prerequisites: MedChem 740
Instructor: Staff
Terms: Winter
Defending an Original Research Proposal (Credits: 1)
The students finalize the research proposal drafted in MedChem 740 and make an oral presentation to their committee.
Prerequisites: MedChem 740
Instructor: Staff
Terms: Winter
Medicinal Chemistry 840
Medicinal Chemistry Seminar (Credits: 1)
Weekly or Bi-weekly Medicinal Chemistry Seminar Series featuring lecturers from University of Michigan, or other outside institutions.
Instructor: Staff
Terms: Fall/Winter
Medicinal Chemistry Seminar (Credits: 1)
Weekly or Bi-weekly Medicinal Chemistry Seminar Series featuring lecturers from University of Michigan, or other outside institutions.
Instructor: Staff
Terms: Fall/Winter
Medicinal Chemistry 990
Dissertation/Precandidacy (Credits: 2-8)
Election for dissertation work by doctoral students not yet admitted to candidacy.
Prerequisites: Advanced doctoral student status
Instructor: Staff
Terms: Fall/Winter
Dissertation/Precandidacy (Credits: 2-8)
Election for dissertation work by doctoral students not yet admitted to candidacy.
Prerequisites: Advanced doctoral student status
Instructor: Staff
Terms: Fall/Winter
Medicinal Chemistry 995
Dissertation-Candidate (Credits: 4-8)
Election for dissertation work by doctoral student admitted to candidacy.
Prerequisites: Doctoral candidacy
Instructor: Staff
Terms: Fall/Winter
Dissertation-Candidate (Credits: 4-8)
Election for dissertation work by doctoral student admitted to candidacy.
Prerequisites: Doctoral candidacy
Instructor: Staff
Terms: Fall/Winter
