Our work aims to assist in the design of new therapeutics through development of theoretical methods, software, and bioinformatics resources for computational studies of organic molecules, peptides and proteins in biological membranes. Our research focuses on the following:

• peptide folding into α-helices and β-sheets in the lipid bilayer
• self-association of transmembrane α-helices  
• binding and spatial arrangement of molecules in membranes
• translocation of structurally diverse molecules across biological membranes.

We developed and continue to update two public databases cataloguing membrane proteins as well as three open-access web servers for modeling peptides, proteins and their complexes in lipid bilayers.