The Medicinal Chemistry Department seminars involve a mix of prominent researchers from both academic institutions and industry presenting research at the forefront of Medicinal Chemistry (broadly defined). They also include presentations from our own students (dissertation defenses & research seminars). The seminars are held remotely on Thursday, weekly at 4:00 p.m. unless otherwise stated. Select a semester from the drop-down menu below to browse the schedule. Remote Seminars for 2020-2021, Zoom links will be announced via e-mail. Please contact the department at COP-MedChemDept@med.umich.edu if you would like to be added to the MedChemSeminars e-mail announcement group.

View a list of all MedChem seminars

September 21, 2022
9:00am
Rackham Building
Nicholas Meanwell, PhD
Vice President, Bristol-Myers Squibb

Annual U-M Drug Discovery Symposium


October 13, 2022
4:00pm
2548 NUB
Adam Shuhendler, PhD
Associate Professor and Canada Research Chair, Department of Chemistry & Biomolecular Sciences; Scientist, University of Ottawa Heart Institute
University of Ottawa

Watching it all go bad: Exploiting dynamic reactivity for molecular imaging

Faculty Host: Peter Scott ( pjhscott@umich.edu )
Speaker Abstract
October 27, 2022
4:00pm
2548 NUB
Mary Kay Pflum, PhD
Professor of Chemistry
Wayne State University

Kinase-catalyzed Labeling: Chemical Approaches to Mapping Cell Signaling Pathways

Faculty Host: Peter Toogood
Speaker Abstract
November 3, 2022
4:00pm
2548 NUB
Erik Hembre, PhD
Associate Vice President Discovery Research and Technologies
Eli Lilly and Co.

Discovery of LY3154885, a Second Generation Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Drug-Drug Interaction Risk Profile

Faculty Host: Peter Toogood
Speaker Abstract
November 4, 2022
4:00pm
CCCB 0420
Shireen Ashkar
Medicinal Chemistry PhD Defense
College of Pharmacy, University of Michigan

Development and Discovery of Novel Inhibitors of Mycobacterium tuberculosis RNA Polymerase for the Treatment of Tuberculosis

Faculty Host: George Garcia ( gagarcia@umich.edu )
Speaker Abstract
November 10, 2022
4:00pm
2548 NUB
Larry Hamann, PhD
Co-Founder and CEO
Interdict Bio

The Arc of Innovation in Small Molecule Drug Discovery: Past, Present & Future


November 10, 2022
2:00pm
Rackham 4th Floor East Conference Room
Nicholas Ragazzone
Medicinal Chemistry PhD Defense
College of Pharmacy, University of Michigan

Elucidating Protein-DNA Recognition by the Bacterial Transcription Factors MarA and VirF by Homology Modeling and DNA-binding Studies of Wild-type and Mutant MarA and VirF

Faculty Host: George Garcia ( gagarcia@umich.edu )
Speaker Abstract
November 16, 2022
1:15pm
Virtual
Garrett Dow
Medicinal Chemistry PhD Defense
College of Pharmacy, University of Michigan

Elucidation of DNA-Binding and Dimerization Activities of the Master Virulence Transcription Factor, VirF, From Shigella flexneri to Aid in Virulence-Targeted Inhibitor Design for Treatment of Shigellosis

Faculty Host: George Garcia ( gagarcia@umich.edu )
Speaker Abstract
November 17, 2022
4:00pm
Palmer Commons Forum Hall
Gunda Georg, PhD
Regents Professor of Medicinal Chemistry, Robert Vince Endowed Chair, McKnight Presidential Chair
University of Minnesota

Discovery and development of a novel contraceptive for men

Faculty Host: Martin Clasby
Speaker Abstract
November 28, 2022
10:00am
LSI Library
Rachel Torrez
Medicinal Chemistry PhD Defense
College of Pharmacy, University of Michigan

Structural and Functional Analysis of Human Dicer

Faculty Host: Amanda Garner ( algarner@umich.edu )
December 15, 2022
4:00pm
2548 NUB
Erika Taylor, PhD
Associate Professor of Chemistry
Wesleyan University

Drug Discovery and E. coli HeptosyltransferaseI - How basic science research might change our understanding of antibiotic mechanism of action

Faculty Host: Peter Toogood
Speaker Abstract
December 16, 2022
9:00am
1544 NUB
Jesse Wotring
Medicinal Chemistry PhD Defense
College of Pharmacy, University of Michigan

Rapidly Translational Drug Discovery Using High Content Imaging: Applications to Non-Alcoholic Fatty Liver Disease and the COVID-19 Pandemic

Faculty Host: Jonny Sexton ( jzsexton@umich.edu )
Speaker Abstract