Pharmaceutical Sciences 519
Pharmaceutical Engineering [Cross-listed with Chemical Engineering 519]
(Credits: 3)

Offered in conjunction with the interdisciplinary Masters of Engineering in Pharmaceutical Engineering (M.Eng.) program, this course covers the concepts necessary to adapt engineering principles to pharmaceutical and life sciences related industries. Topics include process engineering in the drug discovery, high throughput characterization and optimization of new chemical entities, solid-state engineering, and intelligent pharmaceutical manufacturing systems. Lectures, problems, and Internet and library study will be used to develop the ideas presented.

Prerequisites: Senior or graduate standing, permission of instructor.
Instructor: Amidon
Terms: Winter
Pharmaceutical Sciences 568
Investigations in Pharmaceutics
(Credits: 1-6)

Original investigation of a laboratory or library problem to be selected after consultation with the instructor. A paper is required.

Prerequisites: Permission of instructor
Instructor: Staff
Terms: Fall/Winter
Pharmaceutical Sciences 700
Biopharmaceutics and Drug Disposition
(Credits: 3)

Offered alternate Fall Terms. This entry level course is designed for 1st or 2nd year graduate students in the pharmaceutical or related biomedical sciences.  The course focuses on the ADME concepts of absorption, distribution, metabolism, excretion, and basic pharmacokinetic/dynamic modeling, along with  transport, transporters, drug metabolism, and pharmacogenomics.  One and one-half hour lectures are held twice a week. 


Instructor: Smith
Terms: Fall
Pharmaceutical Sciences 701
Equilibria and Dosage Forms
(Credits: 2)

Offered alternate Fall Terms. This course focuses on the physical chemistry of drugs and drug delivery systems.  Thermodynamic principles, solution and interfacial phenomena, solubility, and solid state properties will be emphasized with a focus primarily on small molecules.  These physicochemical principles will be applied to the design, characterization, and performance of a variety of drug delivery systems.      

Prerequisites: Graduate student standing or permission of instructor
Instructor: Amidon
Terms: Fall
Pharmaceutical Sciences 702
Pharmaceutical Design, Delivery and Targeting – Biomolecular Concepts
(Credits: 3)

Offered alternate Fall Terms. This course focuses on the biological and molecular concepts of drug design, delivery and targeting.  The fundamental principles of cell biology and molecular biology will be applied to drug design, targeted drug delivery, and cellular drug delivery.

Prerequisites: Graduate student standing
Instructor: Lee
Terms: Fall
Pharmaceutical Sciences 703
Mass Transport and Chemical Kinetics
(Credits: 2)

Offered alternate fall terms.  This course focuses on the fundamentals of rate processes pertaining to drug delivery.  Rate processes will include both physical (i.e., mass transport processes) and chemical (i.e., degredation of drugs) rates.  An introduction to these concepts will be provided including both qualitative and quantitative treatment.  Regular problem sets will be assigned to re-inforce concepts discussed in class and in the assigned reading.  Mass transfer will be applied to drugs moving in solution, dissolving from solid dosage forms, and traversing polymer and biological membranes.  Decomposition of drugs will be examined in solution, in the solid state, and within dosage forms.       

Prerequisites: Math 216 Differential Equations completed or taken concurrently. Graduate student standing or permission of instructor.
Instructor: Schwendeman
Terms: Fall
Pharmaceutical Sciences 704
Analytical Methods in Drug Delivery
(Credits: 2)

The aim of this course is to present students with a broad range of topics and also in-depth treatment on selected analytical methods and techniques that have been used in the design and characterization of various pharmaceutical products: from small molecules to biologics. 

Prerequisites: Graduate student standing or permission of instructor
Instructor: Cheng
Terms: Fall
Pharmaceutical Sciences 705
Nanotechnology for Drug Delivery
(Credits: 3)

This course will detail recent advances made in the interdisciplinary field of nanomedicine for students with physical, chemical, or biological sciences background.  This course will focus on emerging nanotechnologies, and their biomedical applications, including nanomaterials, nanoparticle-based drug delivery systems, nano-based thranostics, and translation of nanomedicine into clinical trials and commercialization.  

Prerequisites: Graduate students or permission of instructor
Instructor: Staff
Terms: Winter
Pharmaceutical Sciences 706
Biologic Products: Recombinant Proteins, Cell Therapies and Biosimilars
(Credits: 2)

In 2016 the top selling drugs are monoclonal antibodies, and half of the new drugs approved are biopharmaceuticals and numerous biosimilars are being developed.  This class is about how biologic drugs are discovered, manufactured, formulated, analyzed, developed and regulated - now essential information for scientists seeking careers in the pharmaceutical industry.  

Prerequisites: Graduate students
Instructor: Schwendeman
Terms: Fall
Pharmaceutical Sciences 755
Advanced Topics
(Credits: 2)

Advanced Topics in Pharmaceutics


Instructor: Staff
Terms: Fall/Winter
Pharmaceutical Sciences 760
Advanced Pharmacokinetics and Biopharmaceutics
(Credits: 3)

Offered alternate Winter Terms. A continuation of the basic concepts introduced in PharmSci 518 (formerly 464) or PharmSci 700.  The course emphasizes the derivation and use of pharmacokinetic and pharmacodynamic equations, methods of data analysis, and computer applications including the use of WinNonlin and NONMEM.  One and one-half hour lectures are held twice a week.

Prerequisites: Math 216 (Differential Equations) and PharmSci 518 or 700 (Basic Pharmacokinetics); or permission of instructor. A course in statistics would be helpful.
Instructor: Smith
Terms: Winter
Pharmaceutical Sciences 838
Seminar in Pharmaceutics
(Credits: 1)

Reports on current studies in the field of Pharmaceutical Sciences.


Instructor: Staff
Terms: Fall/Winter
Pharmaceutical Sciences 990
Dissertation/Precandidacy
(Credits: 2-8)

Election for dissertation work by doctoral students not yet admitted to candidacy.

Prerequisites: Advanced doctoral student status
Instructor: Staff
Terms: Fall/Winter
Pharmaceutical Sciences 995
Dissertation/Candidacy
(Credits: 4-8)

Election for dissertation work by doctoral students admitted to candidacy.

Prerequisites: Doctoral candidacy
Instructor: Staff
Terms: Fall/Winter