Epidemiology 816

Tuberculosis remains one of the deadliest diseases in the world. Social and operational factors, the growing AIDS epidemic, and increasing drug resistance have dramatically compounded the tuberculosis crisis. This course will review the history, epidemiology, biology, pathogenesis, and clinical management of tuberculosis. It will examine the current issues related to tuberculosis and discuss the complex mechanisms that contribute to the almost unparalleled impact of tuberculosis on global health in the past and present time, including the impact of the emergence of AIDS epidemics. Each session will include a one-hour didactic presentation of the specific topic for the session by the instructor followed by a structured class discussion of reading(s) relevant to the session-specific topics that address emerging methods. In the last session, the students will be asked to present their research proposals on an infectious disease of their primary interests using the concepts and methods learned in this class. While the focus of the lectures will be centered on tuberculosis, the discussions will address the application of general concepts in infectious disease.