Summary

Gordon Amidon earned his MA in mathematics and his PhD in pharmaceutical chemistry from the University of Michigan. His research group has developed approaches for predicting drug absorption in humans prior to human studies. Besides assisting greatly in the design and development of new drugs, this approach provides a basis for setting rational in vitro standards for drug development and approval.

Professor Amidon’s group recently demonstrated that the intestinal mucosal cell peptide transporter can be used to significantly increase the oral absorption of poorly absorbed polar drugs. With this approach, drugs that would otherwise be ineffective by oral administration can be used in the treatment of various human diseases. Additional research areas include oral delivery of peptide and peptide-type drugs, cellular transport and metabolism of peptide-like drugs and prodrugs, drug dissolution and oral drug delivery, viscoelastic properties of polymeric drug delivery systems, modulatable drug delivery systems, and cloning of the intestinal peptide transporter. 


Feature Story
Dr. Gordon Amidon Receives Honorary Doctorate

Dr. Gordon L. Amidon received a Doctor Honoris Causa (Honorary Doctorate) from the Miguel Hernández (UMH) University of Elche in Alicante, Spain on January 28, 2015. The investiture ceremony took place during the celebration of the feast of St. Thomas Aquinas.

Research Interests

  • Drug transport and delivery

Awards

  • 1975 Ebert Prize
  • 1980 Parenteral Drug Association Research Award (as faculty advisor to student of award-winning research paper)
  • 1981 Ebert Prize
  • 1984 Ebert Prize
  • 1996 Scheele Award, Swedish Academy of Pharmaceutical Sciences, for outstanding contributions to the field of oral drug delivery and biopharmaceutics
  • 2001 Honorary Doctor of Pharmacy Degree, Uppsala University, Uppsala, Sweden
  • 2003 Controlled Release Society Founders
  • 2004 Volwiler Research Achievement Award, in recognition of outstanding research achievement by an AACP pharmacy educator
  • 2004 American Association of Pharmaceutical Scientists Meritorious Manuscript Award
  • 2005 American Association of Pharmaceutical Scientists Distinguished Pharmaceutical Scientist Award, AAPS highest award
  • 2006 Federation Internationale Pharmaceutique (FIP) Distinguished Science Award
  • 2006 Gerhard Levy Distinguished Lectureship
  • 2009 Alexander Von Humboldt Research Fellowship Award
  • 2011 Japan Society for the Promotion of Science (JSPS) Research Fellowship Award
  • 2012 Japan Society for the Promotion of Science (JSPS) Takeru Higuchi Award for Pha

Recent Publications

  • Bart Hens; Maura Corsetti; Robin Spiller; Luca Marciani; Tim Vanuytsel; Jan Tack; Arjang Talattof; Gordon L. Amidon; Mirko Koziolek; Werner Weitschies; Clive G. Wilson; Roelof J. Bennink; Joachim Brouwers; Patrick Augustijns Exploring gastrointestinal variables affecting drug and formulation behavior. International Journal of Pharmaceutics. 2017;519(1-2):79-97
  • Fengjuan Cao; Gordon L. Amidon; Nair Rodriguez-Hornedo; Gregory E. Amidon Mechanistic Analysis of Cocrystal Dissolution as a Function of pH and Micellar Solubilization. Molecular Pharmaceutics. 2016;13(3):1030-1046
  • Tuba Incecayir; Jing Sun; Yasuhiro Tsume; Hao Xu; Tomoka Gose; Takeo Nakanishi; Ikumi Tamai; John Hilfinger; Elke Lipka; Gordon L. Amidon Carrier-Mediated Prodrug Uptake to Improve the Oral Bioavailability of Polar Drugs. Journal of Pharmaceutical Sciences. 2016;105(2):925-933
  • Kazuki Matsui; Yasuhiro Tsume; Gregory E. Amidon; Gordon L. Amidon The Evaluation of In Vitro Drug Dissolution of Commercially Available Oral Dosage Forms for Itraconazole in Gastrointestinal Simulator With Biorelevant Media. Journal of Pharmaceutical Sciences. 2016;105(9):2804-2814
  • Kazuki Matsui; Yasuhiro Tsume; Gregory E. Amidon; Gordon L. Amidon The Evaluation of In Vitro Drug Dissolution of Commercially Available Oral Dosage Forms for Itraconazole in Gastrointestinal Simulator With Biorelevant Media. Journal of Pharmaceutical Sciences. 2016;105(9):2804-2814