Selected Publications

  • Shi J, Xiao J, Wang X, Jung SM, Bleske BE, Markowitz JS, Patrick KS, Zhu HJ. Plasma Carboxylesterase 1 Predicts Methylphenidate Exposure: A Proof-of-Concept Study Using Plasma Protein Biomarker for Hepatic Drug Metabolism. Clin Pharmacol Ther. 2022 Apr;111(4):878-885. doi: 10.1002/cpt.2486. Epub 2021 Nov 30. PubMed PMID: 34743324; NIHMSID:NIHMS1816163.

    Li J, Shi J, Xiao J, Tran L, Wang X, Zhu HJ. Contributions of Cathepsin A and Carboxylesterase 1 to the Hydrolysis of Tenofovir Alafenamide in the Human Liver, and the Effect of CES1 Genetic Variation on Tenofovir Alafenamide Hydrolysis. Drug Metab Dispos. 2022 Mar;50(3):243-248. doi: 10.1124/dmd.120.000323. Epub 2021 Dec 21. PubMed PMID: 34933885; PubMed Central PMCID: PMC8969131.

    Her LH, Wang X, Shi J, Choi HJ, Jung SM, Smith LS, Wu AH, Bleske BE, Zhu HJ. Effect of CES1 genetic variation on enalapril steady-state pharmacokinetics and pharmacodynamics in healthy subjects. Br J Clin Pharmacol. 2021 Dec;87(12):4691-4700. doi: 10.1111/bcp.14888. Epub 2021 May 26. PubMed PMID: 33963573.

    Li J, Liu S, Shi J, Zhu HJ. Activation of Tenofovir Alafenamide and Sofosbuvir in the Human Lung and Its Implications in the Development of Nucleoside/Nucleotide Prodrugs for Treating SARS-CoV-2 Pulmonary Infection. Pharmaceutics. 2021 Oct 11;13(10). doi: 10.3390/pharmaceutics13101656. PubMed PMID: 34683949; PubMed Central PMCID: PMC8540046.

    Shi J, Xiao J, Li J, Wang X, Her L, Sorensen MJ, Zhu HJ. FRACPRED-2D-PRM: A Fraction Prediction Algorithm-Assisted 2D Liquid Chromatography-Based Parallel Reaction Monitoring-Mass Spectrometry Approach for Measuring Low-Abundance Proteins in Human Plasma. Proteomics. 2020 Dec;20(24):e2000175. doi: 10.1002/pmic.202000175. Epub 2020 Nov 3. PubMed PMID: 33085175; PubMed Central PMCID: PMC7744362.

    He B, Shi J, Wang X, Jiang H, Zhu HJ. Genome-wide pQTL analysis of protein expression regulatory networks in the human liver. BMC Biol. 2020 Aug 10;18(1):97. doi: 10.1186/s12915-020-00830-3. PubMed PMID: 32778093; PubMed Central PMCID: PMC7418398.

Listing Row

Tuesday, September 23, 2014
Tuesday, September 23, 2014