Selected Publications
Li, J.; de Melo Jorge, D. M.; Wang, W.; Sun, S.; Frum, T.; Hang, Y.-A.; Liu, Y.; Zhou, X.; Xiao, J.; Wang, X. Spence, JR. Wobus, CE. and Zhu, H.J. Differential Bioactivation Profiles of Different GS-441524 Prodrugs in Cell and Mouse Models: ProTide Prodrugs with High Cell Permeability and Susceptibility to Cathepsin A Are More Efficient in Delivering Antiviral Active Metabolites to the Lung. Journal of Medicinal Chemistry 2024.
Bhatt‐Mehta, V.; Jing, X.; Wang, X.; Zhu, H. J. Transplacental methadone exposure and risk of Neonatal Opioid Withdrawal Syndrome. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 2023.
Her, L.; Shi, J.; Wang, X.; He, B.; Smith, L.; Jiang, H.; Zhu, H. J. Identification of regulatory variants of carboxylesterase 1 (CES1): A proof‐of‐concept study for the application of the Allele‐Specific Protein Expression (ASPE) assay in identifying cis‐acting regulatory genetic polymorphisms. Proteomics 2022, 2200176.
Li, J.; Xue, Y.; Wang, X.; Smith, L. S.; He, B.; Liu, S.; Zhu, H. J. Tissue‐and cell‐expression of druggable host proteins provide insights into repurposing drugs for COVID‐19. Clinical and Translational Science 2022.
Shi, J.; Xiao, J.; Wang, X.; Jung, S. M.; Bleske, B. E.; Markowitz, J. S.; Patrick, K. S.; Zhu, H. J. Plasma carboxylesterase 1 predicts methylphenidate exposure: a proof‐of‐concept study using plasma protein biomarker for hepatic drug metabolism. Clinical Pharmacology & Therapeutics 2021.