Dr. Duxin Sun is the Associate Dean for Research in the College of Pharmacy at the University of Michigan. He is the Charles Walgreen Jr. Professor of Pharmacy and Professor of Pharmaceutical Sciences, and serves as the Director of the Pharmacokinetics (PK) Core. Dr. Sun also has a joint appointment in the Chemical Biology program, the Interdisciplinary Medicinal Chemistry program, and University of Michigan's Comprehensive Cancer Center.

Dr. Sun’s research interests focus on drug development, cancer nanomedicine, cancer vaccine, and pharmacokinetics. Dr. Sun developed the STAR system (Structure-Tissue/Cell Selectivity-Activity-Relationship) to enhance drug development success by addressing the 90% failure rate. He also proposed a drug/nanocarrier-specific anticancer nanomedicine design strategy to enhance thier clinical efficacy and improve clinical success.  Dr. Sun earned his BS in Pharmacy, MS in Pharmacology, and PhD in Pharmaceutical Sciences, and has also received training in Molecular Biology as a visiting scientist. With research experience in both academia and the pharmaceutical industry, Dr. Sun has published over 260 papers, and has mentored 40 PhD students and 75 postdoctoral fellows/visiting scientists.

Dr. Sun is an elected Fellow of both the American Association for the Advancement of Science (AAAS) and the American Association of Pharmaceutical Scientists (AAPS). He has served on the FDA Pharmaceutical Science and Clinical Pharmacology Advisory Committee and participated in study sections for the NIH and FDA.

Dr. Sun's administrative Specialist is Erika Zucal - [email protected].

Feature Story
Machine learning- and STAR-guided development of GI-locally activating JAK inhibitor to treat ulcerative colitis

In this study, we integrated machine learning (ML), structure-tissue selectivity-activity-relationship (STAR), - and wet lab synthesis/testing to design a gastrointestinal (GI) locally activating JAK inhibitor for ulcerative colitis treatment.


  • Associate Dean for Research: UM Pharmacy Professor Research Outreach (UM Pharmacy PRO)

Research Interests

Selected Publications