Binita Shrestha
North Campus Research Complex
1600 Huron Parkway
Ann Arbor, MI 48109-1600
Overall Role
To assess in vivo efficacy of a series of novel compounds developed in my laboratory as single-agents and in combination with the standard-of-care chemotherapy for colorectal and pancreatic cancers. Also, to perform in-depth mechanistic studies to better elucidate the mechanism of action of these compounds, develop resistant cell lines, and run RNA-seq and proteomics experiments to identify novel biomarkers. The individual will also be responsible for operation of a specialized lab; develops, designs and conducts one or more large complex research experiments in line with plan; reviews progress and evaluates results. Formulates research methods and suggests options for improving quality, identifies potential problems, recommends and implements solutions; consults with users to refine or adapt methodologies.
Job Functions
- Assess synergy studies in multiple cell lines and develop resistant cell lines
- Molecular pharmacology techniques such as PCR, Western blot, flow cytometry, and microscopy.
- Perform in vivo studies
- Perform RNA-seq
- Report & Manuscript Writting