Research Interests

  • Antimicrobial Pharmacokinetics/Pharmacodynamics in Obesity.

  • Precision Medicine through Treatment Algorithms that rely on Adaptive Feedback Design



  • Population Pharmacokinetic Systems Analyses to Optimize Drug Dosing in Special Populations

  • Drug Interactions in Infectious Diseases (

Selected Publications

  • Pai MP, Cojutti P, Pea F. Pharmacokinetics and pharmacodynamics of continuous
    infusion meropenem in overweight, obese, and morbidly obese patients with
    stable and unstable kidney function: a step toward dose optimization for the 
    treatment of severe gram-negative bacterial infections.
    Clin Pharmacokinet. 2015 Sep;54(9):933-41.
    Pai MP, Neely M, Rodvold KA, Lodise TP. Innovative approaches to optimizing the delivery of vancomycin in individual patients.
    Adv Drug Deliv Rev. 2014 Nov 20;77:50-7.
    Falcone M, Russo A, Venditti M, Novelli A, Pai MP. Considerations for higher doses of daptomycin in critically ill patients with 
    methicillin-resistant Staphylococcus aureus bacteremia. Clin Infect Dis. 2013 Dec;57(11):1568-76. 
    Pai MP. Drug dosing based on weight and body surface area: mathematical assumptions and limitations in obese adults. 
    Pharmacotherapy. 2012 Sep;32(9):856-68. 
    Pai MP, Paloucek FP. The origin of the "ideal" body weight equations. Ann Pharmacother. 2000 Sep;34(9):1066-9.