Research Interests

  • Antimicrobial Pharmacokinetics/Pharmacodynamics in Obesity.

  • Precision Medicine through Treatment Algorithms that rely on Adaptive Feedback Design

  • Population Pharmacokinetic Systems Analyses to Optimize Drug Dosing in Special Populations

Selected Publications

  • Bunnell KL, Pai MP, Sikka M, Bleasdale SC, Wenzler E, Danziger LH, Rodvold KA.
    Pharmacokinetics of Telavancin at Fixed Doses in Normal Body Weight and Obese 
    (Classes I, II, and III) Adult Subjects.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.02475-17.

     

    Miglis C, Rhodes NJ, Avedissian S, Kubin CJ, Yin MT, Nelson B, Pai MP, Scheetz MH.
    Population pharmacokinetics of polymyxin B in acutely ill adult patients.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.01475-17.

     

    Pai MP, Derstine B, Lichty M, Ross B, Sullivan J, Su G, Wang SL.
    Relationships of Vancomycin Pharmacokinetics to Body Size and Composition by Computed Tomography Analysis:
    A novel "Pharmacomorphomic" approach.
    Antimicrob Agents Chemother 2017 24;61(11). pii: e01402-17.

     

    Pai MP. Drug dosing based on weight and body surface area: mathematical assumptions and limitations in obese adults. 
    Pharmacotherapy. 2012 Sep;32(9):856-68.
    
    Pai MP, Paloucek FP. The origin of the "ideal" body weight equations. Ann Pharmacother. 2000 Sep;34(9):1066-9. 

     

    The 4th edition of Drug Interactions in Infectious Diseases (March 2018) is now available in two volumes