Summary

Dr. Pai’s is  Professor of Clinical Pharmacy and Deputy Director of the Pharmacokinetics Core Laboratory  at the University of Michigan. His research focus is optimal drug dose selection in special populations such as obesity. He earned his Pharm.D. from the University of Texas  at Austin and Health Sciences Center in San Antonio, Texas. He completed a pharmacy practice residency at Bassett Healthcare in Cooperstown, New York, and an infectious diseases/pharmacokinetics fellowship at the University of Illinois at Chicago. He has held tenured faculty positions at University of New Mexico and Albany College of Pharmacy. Dr. Pai has over 100 publications and has received multiple awards for his work.

Research Interests

  • Antimicrobial Pharmacokinetics/Pharmacodynamics in Obesity.

  • Precision Medicine through Treatment Algorithms that rely on Adaptive Feedback Design

  • Population Pharmacokinetic Systems Analyses to Optimize Drug Dosing in Special Populations

Awards

  • 2020 Excellence in Achievement, American College of Clinical Pharmacology
  • 2019 Pharmacotherapy Paper of the Year, Society of Infectious Diseases Pharmacists

Selected Publications

  • Crass RL, Pai MP. Estimating Renal Function in Drug Development: Time to Take 
the Fork in the Road. J Clin Pharmacol. 2019 Feb;59(2):159-167.

     

    Crass RL, Dunn R, Hong J, Krop LC, Pai MP. Dosing vancomycin in the super
obese: less is more. J Antimicrob Chemother. 2018 Nov 1;73(11):3081-3086.

     

    Crass RL, Rodvold KA, Mueller BA, Pai MP. Renal Dosing of Antibiotics: Are We 
Jumping the Gun? Clin Infect Dis. 2018 Sep 13. doi: 10.1093/cid/ciy790.

     

    Pai MP, Derstine B, Lichty M, Ross B, Sullivan J, Su G, Wang SL.
Relationships of Vancomycin Pharmacokinetics to Body Size and Composition by Computed Tomography Analysis:
A novel "Pharmacomorphomic" approach.
Antimicrob Agents Chemother 2017 24;61(11). pii: e01402-17.

     

    Pai MP. Drug dosing based on weight and body surface area: mathematical assumptions and limitations in obese adults. 
Pharmacotherapy. 2012 Sep;32(9):856-68.

Pai MP, Paloucek FP. The origin of the "ideal" body weight equations. Ann Pharmacother. 2000 Sep;34(9):1066-9.

     

    The 4th edition of Drug Interactions in Infectious Diseases (March 2018) is now available in two volumes