Publications

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2023

2022

2021

2020

2019

Before 2018

Jennaro, Theodore S., Michael A. Puskarich, Thomas L. Flott, Laura A. McLellan, Alan E. Jones, Manjunath P. Pai, and Kathleen A. Stringer. "Kidney Function as a Key Driver of the Pharmacokinetic Response to High‐Dose L‐Carnitine in Septic Shock."
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy (2023).
Leino, Abbie D., John C. Magee, David B. Kershaw, Manjunath P. Pai, and Jeong M. Park. "A comprehensive mixed‐method approach to characterize the source of diurnal tacrolimus exposure variability in children: Systematic review, meta‐analysis, and application to an existing dataset."
The Journal of Clinical Pharmacology (2023).
Shuhan Liu, Aleksas Matvekas, Tamara Naimi, Aws Ghanem, Ruiting Li, Krishani Rajanayake, Brian Derstine, Brian Ross, June Sullivan, Hyun Gi Yun, Scott Regenbogen, John Byrn, Grace Su, Stewart Wang, Manjunath P. Pai. "Morphomics‐Informed Population Pharmacokinetic and Physiologically‐Based Pharmacokinetic Modeling to Optimize Cefazolin Surgical Prophylaxis."
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy (2023).
Alikhani, Radin, and Manjunath P. Pai. "Reconsideration of the Current Models of Estimated Kidney Function‐based Drug Dose Adjustment in Older Adults: The Role of Biological Age."
Clinical and Translational Science (2023).
Jin, Guang, Jessie W. Ho, Toby Philip Keeney-Bonthrone, Manjunath P. Pai, Bo Wen, Rebecca Ariel Ober, Deanna Dimonte et al. "Prolonging the therapeutic window for valproic acid treatment in a swine model of traumatic brain injury and hemorrhagic shock."
The journal of trauma and acute care surgery
Leino, Abbie D., John Takyi-Williams, and Manjunath P. Pai. "Volumetric Absorptive Microsampling to Enhance the Therapeutic Drug Monitoring of Tacrolimus and Mycophenolic Acid: A Systematic Review and Critical Assessment."
Therapeutic Drug Monitoring (2022). 10-1097.
Pasternak, Amy L., Jeong M. Park, and Manjunath P. Pai. "Predictive Capacity of Population Pharmacokinetic Models for the Tacrolimus Dose Requirements of Pediatric Solid Organ Transplant Recipients."
Therapeutic Drug Monitoring (2022): 10-1097.
Pai, Manjunath P., Pier Giorgio Cojutti, Valentina Gerussi, Paola Della Siega, Carlo Tascini, and Federico Pea. "Linezolid Population Pharmacokinetics to Improve Dosing in Cardiosurgical Patients: Factoring a New Drug–Drug Interaction Pathway."
Clinical Infectious Diseases 76, no. 7 (2023): 1173-1179.
Pai, Manjunath P., Sirima Sitaruno, and Mohamed Abdelnabi. "Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles."
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 43, no. 1 (2023): 35-42.
Yun, Hyun Gi, Andrew JF Smith, Kenneth C. DeBacker, and Manjunath P. Pai. "Estimated glomerular filtration rate with and without race for drug dosing: Cystatin C vs. serum creatinine."
British Journal of Clinical Pharmacology 89, no. 3 (2023): 1207-1210.

Pai, Manjunath P., and Ryan L. Crass."Translation of Pharmacodynamic Biomarkers of Antibiotic Efficacy in Specific Populations to Optimize Doses."
Antibiotics 10, no. 11 (2021): 1368.
Crass, R., T. Al Naimi, B. Wen, E. Souza, S. Murray,M. Pai, and S. Jia."243: Polymyxin B pharmacokinetics in adult CF patients."
Journal of Cystic Fibrosis 20 (2021): S118.
Pai, Manjunath P., Mark Wilcox, Surya Chitra, and Paul McGovern."Safety and efficacy of omadacycline by body mass index in patients with community-acquired bacterial pneumonia: Subanalysis from a randomized controlled trial."
Respiratory medicine 184 (2021): 106442.
Homan, Morgan J., Andrea Franson, Karthik Ravi, Holly Roberts, Manjunath P. Pai, Cai Liu, Miao He, Aleksas Matvekas, Carl Koschmann, and Bernard L. Marini. "Panobinostat penetrates the blood–brain barrier and achieves effective brain concentrations in a murine model."
Cancer Chemotherapy and Pharmacology (2021): 1-8.
Xin Luan, Hebao Yuan, Yudong Song, Hongxiang Hu, Bo Wen, Miao He, Huixia Zhang, Yan Li, Feng Li, Pan Shu, Joseph P Burnett, Nathan Truchan, Maria Palmisano, Manjunath P Pai, Simon Zhou, Wei Gao, Duxin Sun."Reappraisal of anticancer nanomedicine design criteria in three types of preclinical cancer models for better clinical translation."
Biomaterials (2021): 120910.
Glenn K Wakam, Ben E Biesterveld, Manjunath P Pai, Michael T Kemp, Rachel L O’Connell, Krishani L Rajanayake, Kiril Chtraklin, Claire A Vercruysse, Hasan B Alam "A Single Dose of Valproic Acid Improves Neurologic Recovery and Decreases Brain Lesion Size in Swine Subjected to an Isolated Traumatic Brain Injury."
Journal of Trauma and Acute Care Surgery (2021).
Pai, Manjunath P., Mark H. Wilcox, Surya Chitra, and Paul C. McGovern. "Safety and efficacy of omadacycline by BMI categories and diabetes history in two Phase III randomized studies of patients with acute bacterial skin and skin structure infections."
Journal of Antimicrobial Chemotherapy 76, no. 5 (2021): 1315-1322.
Pai, Manjunath P."Antimicrobial dosing in specific populations and novel clinical methodologies: Obesity."
Clinical pharmacology and therapeutics. 109, no. 4 (2021): 942-951.
Falcone, Marco, Francesco Menichetti, Dario Cattaneo, Giusy Tiseo, Sara Baldelli, Valentina Galfo, Alessandro Leonildi, Enrico Tagliaferri, Antonello Di Paolo, and Manjunath P. Pai."Pragmatic options for dose optimization of ceftazidime/avibactam with aztreonam in complex patients."
Journal of Antimicrobial Chemotherapy 76, no. 4 (2021): 1025-1031.
Michael J Rybak, PharmD, MPH, PhD, Jennifer Le, PharmD, MAS, Thomas P Lodise, PharmD, PhD, Donald P Levine, MD, John S Bradley, Catherine Liu, Bruce A Mueller, Manjunath P Pai, Annie-Wong Beringer, Keith A Rodvold, Holly D Maples. "Validity of 2020 vancomycin consensus recommendations and further guidance for practical application."
American Journal of Health-System Pharmacy (2021).
Auriti, Cinzia, Bianca M. Goffredo, Maria P. Ronchetti, Fiammetta Piersigilli, Sara Cairoli, Iliana Bersani, Andrea Dotta, Pietro Bagolan, and Manjunath P. Pai."High-dose micafungin in neonates and young infants with invasive candidiasis: Results of a phase 2 study."
Antimicrobial agents and chemotherapy 65, no. 4 (2021): e02494-20.
Biesterveld, Ben E., Rachel O’Connell, Michael T. Kemp, Glenn K. Wakam, Aaron M. Williams, Manjunath P. Pai, and Hasan B. Alam. "Validation of intraosseous delivery of valproic acid in a swine model of polytrauma."
Trauma surgery & acute care open 6, no. 1 (2021): e000683.
Ravi, Karthik, Andrea Franson, Morgan J. Homan, Holly Roberts, Manjunath P. Pai, Zachary Miklja, Miao He et al. "Comparative pharmacokinetic analysis of the blood-brain barrier penetration of dasatinib and ponatinib in mice."
Leukemia & Lymphoma (2021): 1-6.
Pai, Manjunath P."Antimicrobial Dosing in Specific Populations and Novel Clinical Methodologies: Kidney Function."
Clinical pharmacology and therapeutics.
He, Miao, Ernane Souza, Aleksas Matvekas, Ryan L. Crass, and Manjunath P. Pai."Alteration in the Acute Kidney Injury Potential with the Combination of Vancomycin and Imipenem-Cilastatin/Relebactam or Piperacillin/Tazobactam in a Preclinical Model."
Antimicrobial agents and chemotherapyAAC-02141.
Wakam, Glenn K., Ben E. Biesterveld, Manjunath P. Pai, Michael T. Kemp, Rachel L. O'Connell, Aaron M. Williams, Ashok Srinivasan et al. "Administration of valproic acid in clinically approved dose improves neurologic recovery and decreases brain lesion size in swine subjected to hemorrhagic shock and traumatic brain injury."
The journal of trauma and acute care surgery 90, no. 2 (2021): 346-352.

Falcone, Marco, Francesco Menichetti, Dario Cattaneo, Giusy Tiseo, Sara Baldelli, Valentina Galfo, Alessandro Leonildi, Enrico Tagliaferri, Antonello Di Paolo, and Manjunath P. Pai."Pragmatic options for dose optimization of ceftazidime/avibactam with aztreonam in complex patients."
Journal of Antimicrobial Chemotherapy (2020).
Ben E Biesterveld, Luke Pumiglia, Ariella Iancu, Alizeh A Shamshad, Henriette A Remmer, Ali Z Siddiqui, Rachel L O’Connell, Glenn K Wakam, Michael T Kemp, Aaron M Williams, Manjunath P Pai, Hasan B Alam"Valproic acid treatment rescues injured tissues after traumatic brain injury."
Journal of Trauma and Acute Care Surgery (2020).
Michael J Rybak, Jennife Le, Thomas P Lodise, Donald P Levine, John S Bradley, Catherine Liu, Bruce A Mueller, Manjunath P Pai, Annie-Wong Beringer, Keith A Rodvold, Holly D Maples "Questions on Vancomycin dosing."
Clinical infectious diseases: an official publication of the Infectious Diseases Society of America no. 6 (2020): 1156-1165.
Wakam, Glenn K., Ben E. Biesterveld, Manjunath P. Pai, Michael T. Kemp, Rachel L. O’Connell, Aaron M. Williams, Ashok Srinivasan et al.."ADMINISTRATION OF VALPROIC ACID IN CLINICALLY APPROVED DOSE IMPROVES NEUROLOGIC RECOVERY AND DECREASES BRAIN LESION SIZE IN SWINE SUBJECTED TO HEMORRHAGIC SHOCK AND TRAUMATIC BRAIN INJURY."
Journal of Trauma and Acute Care Surgery (2020).
Ranjit K Mehta, Sanjima Pal, Koushik Kondapi, Merna Sitto, Cuyler Dewar, Theresa Devasia, Matthew J Schipper, Dafydd G Thomas, Venkatesha Basrur, Manjunath P Pai, Yoshihiro Morishima, Yoichi Osawa, William B Pratt, Theodore S Lawrence, Mukesh K Nyati. "Low-Dose Hsp90 Inhibitor Selectively Radiosensitizes HNSCC and Pancreatic Xenografts."
Clinical Cancer Research: an Official Journal of the American Association for Cancer Research(2020).
Jennaro, Theodore S., Michael A. Puskarich, Marc R. McCann, Christopher E. Gillies, Manjunath P. Pai, Alla Karnovsky, Charles R. Evans, Alan E. Jones, and Kathleen A. Stringer."Using L‐Carnitine as a Pharmacologic Probe of the Interpatient and Metabolic Variability of Sepsis."
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 40, no. 9 (2020): 913-923.
Pai, Manjunath P., and Kenneth C. Debacker. "Modeling Kinetic Glomerular Filtration Rate in Adults with Stable and Unstable Kidney Function: Vancomycin as the Motivating Example."
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy (2020).
Zachary Miklja, Viveka Nand Yadav, Rodrigo T Cartaxo, Ruby Siada, Chase C Thomas, Jessica R Cummings, Brendan Mullan, Stefanie Stallard, Alyssa Paul, Amy K Bruzek, Kyle Wierzbicki, Tao Yang, Taylor Garcia, Ian Wolfe, Marcia Leonard, Patricia L Robertson, Hugh JL Garton, Daniel R Wahl, Hemant Parmar, Jann N Sarkaria, Cassie Kline, Sabine Mueller, Theodore Nicolaides, Chana Glasser, Sarah ES Leary, Sriram Venneti, Chandan Kumar-Sinha, Arul M Chinnaiyan, Rajen Mody, Manjunath P Pai, Timothy N Phoenix, Bernard L Marini, Carl Koschmann. "Everolimus improves the efficacy of dasatinib in PDGFRα-driven glioma."
The Journal of Clinical Investigation 130, no. 10 (2020).
Russo, Rachel, Michael Kemp, Umar F. Bhatti, Manjunath Pai, Glenn Wakam, Ben Biesterveld, and Hasan B. Alam."Life on the Battlefield: Valproic Acid for Combat Applications."
Journal of Trauma and Acute Care Surgery (2020).
Leino, Abbie D., and Manjunath P. Pai. "Maintenance Immunosuppression in Solid Organ Transplantation: Integrating Novel Pharmacodynamic Biomarkers to Inform Calcineurin Inhibitor Dose Selection."
Clinical Pharmacokinetics (2020): 1-18.
Michael J Rybak, Jennifer Le, Thomas P Lodise, Donald P Levine, John S Bradley, Catherine Liu, Bruce A Mueller, Manjunath P Pai, Annie Wong-Beringer, John C Rotschafer, Keith A Rodvold, Holly D Maples, Benjamin M Lomaestro. "Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists."
American Journal of Health-System Pharmacy 77, no. 11 (2020): 835-864.
Pan Shu, Ting Zhao, Bo Wen, Kari Mendelsohn-Victor, Duxin Sun, Christopher R Friese,Manjunath P Pai."Application of an innovative high-throughput liquid chromatography-tandem mass spectrometry method for simultaneous analysis of 18 hazardous drugs to rule out accidental acute chemotherapy exposures in health care workers."
Journal of Oncology Pharmacy Practice 26, no. 4 (2020): 794-802.
Souza, Ernane, Ryan L. Crass, Jeremy Felton, Kengo Hanaya, and Manjunath P. Pai. "Accumulation of major linezolid metabolites in patients with renal impairment."
Antimicrobial Agents and Chemotherapy 64, no. 5 (2020).
Michael J Rybak, Jennifer Le, Thomas P Lodise, Donald P Levine, John S Bradley, Catherine Liu, Bruce A Mueller, Manjunath P Pai, Annie Wong‐Beringer, John C Rotschafer, Keith A Rodvold, Holly D Maples, Benjamin M Lomaestro. "Executive Summary: Therapeutic Monitoring of Vancomycin for Serious Methicillin‐Resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review of the American Society of Health‐System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists."
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 40, no. 4 (2020): 363-367.
Manjunath P Pai, Kenneth C Debacker, Brian Derstine, June Sullivan, Grace L Su, Stewart C Wang. "Comparison of Body Size, Morphomics, and Kidney Function as Covariates of High‐Dose Methotrexate Clearance in Obese Adults with Primary Central Nervous System Lymphoma."
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy (2020).
Cindy H Hsu, Mohamad H Tiba, Brendan M McCracken, Carmen I Colmenero, Zachary Pickell, Danielle C Leander, Anne M Weitzel, Sarita Raghunayakula, Jinhui Liao, Tulasi Jinka, Brandon C Cummings, Manjunath P Pai, Hasan B Alam, Kevin R Ward, Thomas H Sanderson, Robert W Neumar "Dose optimization of early high-dose valproic acid for neuroprotection in a swine cardiac arrest model"
Resuscitation Plus 1 (2020): 100007.
Thomas J Wubben, Mercy Pawar, Eric Weh, Andrew Smith, Peter Sajjakulnukit, Li Zhang, Lipeng Dai, Heather Hager, Manjunath P Pai, Costas A Lyssiotis, Cagri G Besirli "Small molecule activation of metabolic enzyme pyruvate kinase muscle isozyme 2, PKM2, circumvents photoreceptor apoptosis."
Scientific Reports 10, no. 1 (2020): 1-16.
Souza, Ernane, Jeremy Felton, Ryan L. Crass, Kengo Hanaya, and Manjunath P. Pai. "Development of a sensitive LC–MS/MS method for quantification of linezolid and its primary metabolites in human serum."
Journal of pharmaceutical and biomedical analysis 178 (2020): 112968.
Zachary Miklja, Viveka Nand Yadav, Rodrigo T Cartaxo, Ruby Siada, Chase C Thomas, Jessica R Cummings, Brendan Mullan, Stefanie Stallard, Alyssa Paul, Amy K Bruzek, Kyle Wierzbicki, Tao Yang, Taylor Garcia, Ian Wolfe, Marcia Leonard, Patricia L Robertson, Hugh JL Garton, Daniel R Wahl, Hemant A Parmar, Jann N Sarkaria, Cassie Kline, Sabine Mueller, Theodore Nicolaides, Chana Glasser, Sarah ES Leary, Sriram Venneti, Chandan Kumar-Sinha, Arul M Chinnaiyan, Rajen Mody, Manjunath P Pai, Timothy N Phoenix, Bernard L Marini, Carl Koschmann"Everolimus improves the efficacy of dasatinib in PDGFRα-driven glioma."
medRxiv (2020): 2019-12.
Valerie J Morley, Clare L Kinnear, Derek G Sim, Samantha N Olson, Lindsey M Jackson, Elsa Hansen, Grace A Usher, Scott A Showalter, Manjunath P Pai, Robert J Woods, Andrew F Read "An adjunctive therapy approach prevents antibiotic resistance emergence in opportunistic pathogens colonizing the gut"
bioRxiv (2020).
Yu, Alex, Mark J. Koenigsknecht, Bart Hens, Jason R. Baker, Bo Wen, Trachette L. Jackson, Manjunath P. Pai, William Hasler, Gordon L. Amidon, and Duxin Sun. "Mechanistic Deconvolution of Oral Absorption Model with Dynamic Gastrointestinal Fluid to Predict Regional Rate and Extent of GI Drug Dissolution."
The AAPS journal, no. 1 (2020): 3.

Dunn, Ryan D., Ryan L. Crass, Joseph Hong, Manjunath P. Pai, and Lynne C. Krop. "Vancomycin volume of distribution estimation in adults with class III obesity."
American Journal of Health-System Pharmacy 76, no. 24 (2019): 2013-2018.
Rodvold, Keith A., Rodrigo M. Burgos, Xing Tan, and Manjunath P. Pai. "Omadacycline: A Review of the Clinical Pharmacokinetics and Pharmacodynamics."
Clinical pharmacokinetics(2019): 1-17.
Xin Luan, Hebao Yuan, Bo Wen, Wei Gao, Huixia Zhang, Miao He1 Yan Li, Feng Li, Joseph P Burnett, Nathan Truchan, Hongxiang Hu, Pan Shu, Maria Palmisano, Manjunath P Pai, Simon Zhou, Duxin Sun"Investigate Current Anticancer Nanomedicine Design Principles and Identify New Criteria to Improve Clinical Efficacy and Safety."
(2019).
Cindy H Hsu , Mohamad H Tiba , Brendan M McCracken , Carmen I Colmenero , Zachary Pickell , Danielle C Leander , Anne M Weitzel , Tulasi Jinka , Brandon C Cummings , Manjunath P Pai , Kevin R Ward , Robert W Neumar Dose Optimization of Early High-Dose Valproic Acid for Neuroprotection After Cardiac Arrest
Circulation, (2019) ;140:A272
Jang, Soo Min, Manjunath P. Pai, Alexander R. Shaw, and Bruce A. Mueller. "Antibiotic Exposure Profiles in Trials Comparing Intensity of Continuous Renal Replacement Therapy."
Critical Care Medicine47, no. 11 (2019): e863-e871.
Ben E Biesterveld, Aaron M Williams, Manjunath P Pai, Isabel S Dennahy, Nathan J Graham, Kiril Chtraklin, Ali Z Siddiqui, Rachel L O'Connell, Umar F Bhatti, Baoling Liu, Rachel M Russo, Yongqing Li, Hasan B Alam"Dose optimization of valproic acid in a lethal model of traumatic brain injury, hemorrhage, and multiple trauma in swine."
In Open Forum Infectious Diseases , vol. 6. 2019.
Pai, Manjunath P., Mark H. Wilcox, Marla Curran, Surya Chitra, Lynne Garrity-Ryan, and Paul C. McGovern."700. Safety and Efficacy of Omadacycline in Patients with Diabetes in Phase 3 Clinical Studies."
Antimicrobial agents and chemotherapy (2019).
Barks, John DE, Yiqing Liu, Lu Wang, Manjunath P. Pai, and Faye S. Silverstein. "Repurposing azithromycin for neonatal neuroprotection."
Pediatric research 86, no. 4 (2019): 444-451.
Crass, Ryan L., and Manjunath P. Pai. "Optimizing Estimated Glomerular Filtration Rate to Support Adult to Pediatric Pharmacokinetic Bridging Studies in Patients with Cystic Fibrosis."
Clinical pharmacokinetics58, no. 10 (2019): 1323-1332.
P Shu, T Zhao, B Wen, K Mendelsohn-Victor, D Sun, CR Friese, MP Pai . Application of an innovative high-throughput liquid chromatography-tandem mass spectrometry method for simultaneous analysis of 18 hazardous drugs to rule out accidental acute chemotherapy exposures in health care workers
Journal of Oncology Pharmacy Practice (2019): 1078155219870591.
Biesterveld, Ben E., Aaron M. Williams, Manjunath P. Pai , Isabel S. Dennahy, Nathan J. Graham, Kiril Chtraklin, Ali Z. Siddiqui et al. Dose optimization of valproic acid in a lethal model of traumatic brain injury, hemorrhage and polytrauma in swine.
Journal of trauma and acute care surgery (2019).
Jang, Soo Min, Manjunath P. Pai , Alexander R. Shaw, and Bruce A. Mueller. Antibiotic Exposure Profiles in Trials Comparing Intensity of Continuous Renal Replacement Therapy.
Critical Care Medicine (2019).
Rodvold, Keith A., and Manjunath P. Pai .
Clinical Infectious Diseases 69, no. Supplement_1 (2019): S16-S22.
Melby, Daniel P., Charles Gornick, Raed Abdelhadi, Jay Sengupta, Manju Pai , John S. Zakaib, JoEllyn Moore, and David G. Benditt. Outcomes following persistent atrial fibrillation ablation using localized sources identified with Ripple map.
Journal of cardiovascular electrophysiology (2019)
Bland, C. M., M. P. Pai , and T. P. Lodise. Reappraisal of Contemporary Pharmacokinetic and Pharmacodynamic Principles for Informing Aminoglycoside Dosing (vol 38, pg 1229, 2018).
PHARMACOTHERAPY 39, no. 7 (2019): 794-794.
Li, F., H. Yuan, H. Zhang, M. He, J. Liao, N. Chen, Y. Li et al.Neonatal Fc Receptor (FcRn) Enhances Tissue Distribution and Prevents Excretion of nab-Paclitaxel.
Molecular pharmaceutics 16, no. 6 (2019): 2385-2393.
Crass, R. L., P. G. Cojutti, M. P. Pai , and F. Pea. A Reappraisal of Linezolid Dosing in Renal Impairment to Improve Safety.
Antimicrobial agents and chemotherapy (2019).
Barks, John DE, Yiqing Liu, Lu Wang, Manjunath P. Pai , and Faye S. Silverstein. Repurposing azithromycin for neonatal neuroprotection.
Pediatric research (2019): 1.
Dean, Michael, Gabrielle Costello, Ernane Souza, Jeremy Felton, Balazs Szamosfalvi, Manjunath Pai , and Amy Pai. CHARACTERIZATION OF METOPROLOL PARENT AND METABOLITE CONCENTRATIONS PRE AND POST DIALYSIS: IMPLICATIONS FOR INTRADIALYTIC HYPOTENSION AND POST DIALYSIS FATIGUE.
AMERICAN JOURNAL OF KIDNEY DISEASES, vol. 73, no. 5, pp. 715-715. 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA: WB SAUNDERS CO-ELSEVIER INC, 2019.
Zachary Miklja, Brendan Mullan, Stefanie Stallard, Viveka Nand Yadav, Amy K Bruzek, Taylor Garcia, Marcia Leonard, Patricia L Robertson, Alyssa Paul, Manjunath P Pai , Timothy Phoenix, Bernard Marini, Carl Koschmann HGG-05. GALLIUM MALTOLATE AS TREATMENT IN PEDIATRIC GLIOMA
Neuro-Oncology (2019): 1-10.
Crass, Ryan L., and Manjunath P. Pai . Optimizing Estimated Glomerular Filtration Rate to Support Adult to Pediatric Pharmacokinetic Bridging Studies in Patients with Cystic Fibrosis.
Clinical pharmacokinetics (2019): 1078155219870591.
Crass, Ryan L., and Manjunath P. Pai .Pharmacokinetics and Pharmacodynamics of β‐Lactamase Inhibitors.
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 39, no. 2 (2019): 182-195.
Crass, Ryan L., and Manjunath P. Pai . Estimating renal function in drug development: time to take the fork in the road.
The Journal of Clinical Pharmacology 59.2 (2019): 159-167.

Bland, Christopher M., Manjunath P. Pai , and Thomas P. Lodise.Reappraisal of Contemporary Pharmacokinetic and Pharmacodynamic Principles for Informing Aminoglycoside Dosing.
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 38, no. 12 (2018): 1229-1238.
Crass, Ryan L., Praveen Kumar, Twisha S. Patel, and Manjunath P. Pai . Piperacillin/tazobactam Therapeutic Drug Monitoring: True Inter-patient Variability or Compound Instability?
Age (years) 69, no. 54 (2018): 72.
Auriti, Cinzia, Bianca Maria Goffredo, Maria Paola Ronchetti, Fiammetta Piersigilli, Sara Cairoli, Iliana Bersani, Andrea Dotta, and Manjunath P. Pai . Validation of heel stick microsampling to optimize micafungin doses in neonates and young infants.
Antimicrobial agents and chemotherapy 62, no. 10 (2018): e01199-18.
Crass, Ryan L., Manjunath P. Pai , and Thomas P. Lodise Jr. Individualizing piperacillin/tazobactam dosing in adult patients with cystic fibrosis: can tobramycin measurements help?.
Journal of Antimicrobial Chemotherapy 74, no. 1 (2018): 126-129.
Crass, Ryan L., Keith A. Rodvold, Bruce A. Mueller, and Manjunath P. Pai . Renal Dosing of Antibiotics: Are We Jumping the Gun?.
Clinical Infectious Diseases 68, no. 9 (2018): 1596-1602.
Crass, Ryan L., Ryan Dunn, Joseph Hong, Lynne C. Krop, and Manjunath P. Pai . Dosing vancomycin in the super obese: less is more.
Journal of Antimicrobial Chemotherapy 73, no. 11 (2018): 3081-3086.
Li, Feng, Huixia Zhang, Miao He, Jinhui Liao, Nianhang Chen, Yan Li, Simon Zhou et al. Different nanoformulations alter the tissue distribution of paclitaxel, which aligns with reported distinct efficacy and safety profiles."
Molecular pharmaceutics 15, no. 10 (2018): 4505-4516.
Butterfield‐Cowper, Jill M., Thomas P. Lodise Jr, and Manjunath P. Pai . A Fixed versus Weight‐Based Dosing Strategy of Daptomycin May Improve Safety in Obese Adults.
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 38, no. 9 (2018): 981-985.
Pai, Amy Barton, Manjunath P. Pai , Dan E. Meyer, Brian C. Bales, Victoria E. Cotero, Nan Zheng, and Wenlei Jiang. In vitro and in vivo DFO-chelatable labile iron release profiles among commercially available intravenous iron nanoparticle formulations.
Regulatory Toxicology and Pharmacology 97 (2018): 17-23.
Hertz, Daniel L., Kelley M. Kidwell, Kiran Vangipuram, Feng Li, Manjunath P. Pai , Monika Burness, Jennifer J. Griggs et al.Paclitaxel plasma concentration after the first infusion predicts treatment-limiting peripheral neuropathy.
Clinical Cancer Research 24, no. 15 (2018): 3602-3610.
Cojutti, Piergiorgio, Manjunath P. Pai , and Federico Pea. Population pharmacokinetics and dosing considerations for the use of linezolid in overweight and obese adult patients.
Clinical pharmacokinetics 57, no. 8 (2018): 989-1000.
Ma, Zhuo, Erica Lasek-Nesselquist, Jackson Lu, Ryan Schneider, Riddhi Shah, George Oliva, Janice Pata et al. Characterization of genetic changes associated with daptomycin nonsusceptibility in Staphylococcus aureus.
PloS one, 13(6), p.e0198366.
Crass, Ryan L., Brian E. Ross, Brian A. Derstine, Matt Lichty, June A. Sullivan, Grace L. Su, Stewart C. Wang, and Manjunath P. Pai . Measurement of skeletal muscle area improves estimation of aminoglycoside clearance across body size.
Antimicrobial agents and chemotherapy 62, no. 6 (2018): e00441-18.
Eschenauer, Gregory A., Peggy L. Carver, Twisha S. Patel, Shu-Wen Lin, Kenneth P. Klinker, Manjunath P. Pai , and Simon W. Lam. Survival in patients with Candida glabrata bloodstream infection is associated with fluconazole dose.
Antimicrobial agents and chemotherapy 62, no. 6 (2018): e02566-17.
Bunnell, Kristen L., Manjunath P. Pai , Monica Sikka, Susan C. Bleasdale, Eric Wenzler, Larry H. Danziger, and Keith A. Rodvold. Pharmacokinetics of telavancin at fixed doses in normal-body-weight and obese (Classes I, II, and III) adult subjects.
Antimicrobial agents and chemotherapy 62, no. 4 (2018): e02475-17.
Benjamin, Emelia J., Salim S. Virani, Clifton W. Callaway, Alanna M. Chamberlain, Alexander R. Chang, Susan Cheng, Stephanie E. Chiuve et al. Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association.
Circulation 137, no. 12 (2018): e67-e492.
Pai, Manjunath P. , Jennifer J. Kiser, Paul O. Gubbins, and Keith A. Rodvold, eds. Drug Interactions in Infectious Diseases: Antimicrobial Drug Interactions.
Springer, 2018.
Falcone, Marco, Pierluigi Viale, Giusy Tiseo, and Manjunath Pai . Pharmacokinetic drug evaluation of avibactam+ ceftazidime for the treatment of hospital-acquired pneumonia.
Expert opinion on drug metabolism & toxicology 14, no. 3 (2018): 331-340.
Miglis, Cristina, Nathaniel J. Rhodes, Sean N. Avedissian, Christine J. Kubin, Michael T. Yin, Brian C. Nelson, Manjunath P. Pai , and Marc H. Scheetz.Population pharmacokinetics of polymyxin B in acutely ill adult patients.
Antimicrobial agents and chemotherapy 62, no. 3 (2018): e01475-17.
Georgoff, Patrick E., Vahagn C. Nikolian, Tess Bonham, Manjunath P. Pai , Celia Tafatia, Ihab Halaweish, Kathleen To et al.Pharmacokinetics and Safety of High-Dose Intravenous Valproic Acid in Healthy Subjects: A Dose Escalation Trial To Support Clinical Translational Studies.
Clinical pharmacokinetics 57, no. 2 (2018): 209.
Georgoff, Patrick E., Vahagn C. Nikolian, Tess Bonham, Manjunath P. Pai , Celia Tafatia, Ihab Halaweish, Kathleen To et al.Safety and tolerability of intravenous valproic acid in healthy subjects: a phase I dose-escalation trial.
Clinical pharmacokinetics 57, no. 2 (2018): 209-219.
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