LABORATORY

Guizhi (Julian) Zhu Laboratory

Guizhi (Julian) Zhu

Guizhi (Julian) Zhu, PhD

B.S.: Nankai University, China
Ph.D.: University of Florida, USA
Postdoc training: National Institutes of Health, USA

The research in my lab lies at the interface of immunology, nucleic acid engineering, and functional biomaterials. Our current focus is to develop novel circRNA/mRNA/oligonucleotides immunotherapeutics and vaccines and their delivery systems for the prophylaxis and immunotherapy of cancer, infectious diseases, and autoimmune disorders. Our research has been funded by federal and foundation grants from National Institutes of Health (NIH), Department of Defense (DoD), and American Cancer Society (ACS).

Lab and Research Overview

Our research interests lie at the interface of immune-oncology, nucleic acid theranostics, immunotherapy, and functional biomaterials. My current focus is to develop therapeutics and vaccines for combination cancer immunotherapy, infectious disease prevention, and drug abuse treatment. Current primary research directions are listed below.

  • mRNA vaccines for cancer immunotherapy and infectious disease prophylaxis.
  • Novel nucleic acid immunotherapeutics for cancer immunotherapy (immunomodulatory DNA/RNA, mRNA, gene-editing gRNA, siRNA, aptamer)
  • ADAR-targeted nucleic acid theranostics and immunomodulators
  • Drug and vaccine delivery
  • Biomaterials: Nanovaccine/Nanomedicine, polymer microneedle patches, hydrogel

Lab Members

Jordan Dailey

Jordan Dailey, PhD

Research Specialist
Wenhua Li

Wenhua Li, MS

Research Lab Tech
You  Xu

You Xu, PhD

Research Fellow
Qiyan Wang

Qiyan Wang, PhD

Research Fellow
Ri Tang

Ri Tang, MD

Research Fellow
Yu Hao

Yu Hao, PhD

Research Fellow
Shimiao Liao

Shimiao Liao, PhD

Research Fellow
Guolan Xiao

Guolan Xiao, PhD

Research Fellow
Sicong Ma

Sicong Ma, PhD

Research Fellow
Ting Xu

Ting Xu, PhD

Research Fellow
Rong Zheng

Rong Zheng, MD

Visiting Research Fellow
Qiwei Yao

Qiwei Yao, MD

Visiting Research Fellow
Zitong Wang

Zitong Wang, BS

PhD student
Qing Sun

Qing Sun, MS

PhD student (co-mentored with Dr. Moon)
Xiang Liu

Xiang Liu, MS

PhD student
Shurong Zhou

Shurong Zhou, MS

PhD student
Erica Liang

Erica Liang, PharmD student