DIRECTORY
Medicinal Chemistry
Meet the Medicinal Chemistry Team
Toogood, Peter , PhD
Research Associate Professor and Director of Michigan Drug Discovery (MDD)
Research Topics
The goal of our medicinal research is to discover new biologically active molecules for the potential treatment of challenging diseases such as pancreatic cancer and myalgic encephalomyelitis/chronic fatigue syndrome. Our approach employs computational chemistry methods, as well as batch and continuous flow organic synthesis.
Traynor, John
Edward F Domino Research Professor and Professor of Medicinal Chemistry, College of Pharmacy Professor and Associate Chair for Research, Department of Pharmacology, Medical School
Tripathi, Ashootosh
Director, UM-Natural Products Discovery Core; Associate Research Scientist, Life Sciences Institute; Research Associate Professor of Medicinal Chemistry, College of Pharmacy
Research Topics
My research directly addresses the eminent health threat lurking over human race due to absence of any plausible next generation antibiotic/ anticancer candidate in the clinical pipeline. I use a multipronged strategy to discover and characterize novel drug leads from microbial cultures by using sophisticated mainstream techniques as well as through harnessing the complete biosynthetic potential of cryptic or minimally expressed secondary metabolite gene clusters. In addition, unique target based approaches are also envisaged to identify potent anticancer, antiviral, antidiabetic, and antibiotic inhibitors, which complements the aforementioned strategy and comprehensively exploits the secondary metabolite capability of microbes for obtaining new druggable molecular entities.